M4659

Milrinone

≥97% (TLC), powder, phosphodiesterase type III inhibitor

• Sinónimos: 1,6-Dihydro-2-methyl-6-oxo-(3,4′-bipyridine)-5-carbonitrile
• Fórmula empírica (notación de Hill): C₁₂H₉N₃O
• Número CAS: 78415-72-2
• Peso molecular: 211.22
• NACRES: NA.77
• PubChem Substance ID: 24278060
• UNSPSC Code: 41106305
• EC Number: 278-903-6
• MDL number: MFCD00133539
• Assay: ≥97% (TLC)
• Form: powder

Propiedades

• Nombre del producto: Milrinone, ≥97% (TLC), powder
• Quality Segment: 200
• assay: ≥97% (TLC)
• form: powder
• solubility: DMSO: >10 mg/mL, H₂O: insoluble
• originator: Sanofi Aventis
• storage temp.: 2-8°C
• SMILES string: CC1=C(C=C(C#N)C(=O)N1)c2ccncc2
• InChI: 1S/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,(H,15,16)
• InChI key: PZRHRDRVRGEVNW-UHFFFAOYSA-N
• Gene Information: human ... PDE3A(5139), PDE3B(5140), PDE4B(5142), PDE5A(8654), PTPRA(5786) ; rat ... Pde3a(50678)

Descripción

Biochem/physiol Actions

Phosphodiesterase type III inhibitor; cAMP-specific, cGMP-inhibitable; potent cardiotonic, positive inotropic vasodilator.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P330 + P331 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges