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M4155

Sigma-Aldrich

Anti-Mouse IgG (Fab specific) antibody produced in goat

2.0 mg/mL, affinity isolated antibody

Sinónimos:

Anti-Mouse Fab Antibody, Anti-Mouse Fab Antibody - Anti-Mouse IgG (Fab specific) antibody produced in goat

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About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.46
En este momento no podemos mostrarle ni los precios ni la disponibilidad

origen biológico

goat

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

secondary antibodies

clon

polyclonal

concentración

2.0 mg/mL

técnicas

Ouchterlony double diffusion: suitable
indirect ELISA: 1:15,000

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

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Descripción general

IgG consists of four polypeptide chains, made of two identical 50 kDa γ heavy (H) chains and two identical 25 kDa κ or λ light (L) chains, which are connected by inter-chain disulfide bonds. IgG has four isotypes IgG1, IgG2, IgG3 and IgG4.

Aplicación

Anti-Mouse IgG (Fab specific) antibody produced in goat has been used in the expression and purification of human platelet factor 4 (PF4) and anti-PF4 monoclonal antibodies.
Anti-Mouse IgG (Fab specific) antibody produced in goat was used as secondary antibody in immunocytochemical staining at a dilution of 1:10.

Acciones bioquímicas o fisiológicas

IgG activates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a critical role in antibody-dependent cell-mediated cytotoxicity (ADCC). It has the longest serum half life and might be associated with allergy.
IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. It provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

Otras notas

Antibody adsorbed with bovine, equine and human serum proteins.

Forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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