I2753
Inosine 3′:5′-cyclic monophosphate sodium salt
≥98%
Sinónimos:
cIMP
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About This Item
Fórmula lineal:
C10H10N4O7PNa
Número de CAS:
Peso molecular:
352.17
Número MDL:
Código UNSPSC:
41106305
ID de la sustancia en PubChem:
NACRES:
NA.51
Productos recomendados
Nivel de calidad
Ensayo
≥98%
Formulario
powder
temp. de almacenamiento
−20°C
cadena SMILES
[Na].OC1C2OP(O)(=O)OCC2OC1n3cnc4C(=O)N=CNc34
InChI
1S/C10H11N4O7P.Na.H/c15-6-7-4(1-19-22(17,18)21-7)20-10(6)14-3-13-5-8(14)11-2-12-9(5)16;;/h2-4,6-7,10,15H,1H2,(H,17,18)(H,11,12,16);;
Clave InChI
XIUBZBACWHALEW-UHFFFAOYSA-N
Aplicación
Inosine 3′:5′-cyclic monophosphate (cIMP) is used in studies that compare the substrate specificity and activity of cyclic purines, including the 3′,5′-cyclic monophosphates cAMP and cGMP.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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Adam K Jagielski et al.
Archives of biochemistry and biophysics, 404(2), 186-196 (2002-07-31)
The effects of extracellular purinergic agonists and their breakdown products on glucose and glutamine synthesis in rabbit kidney-cortex tubules incubated with aspartate + glycerol or alanine + glycerol + octanoate were investigated. A rapid extracellular degradation of ATP was accompanied
Riegel et al.
The Journal of experimental biology, 201 (Pt 24), 3411-3418 (1998-11-18)
External application of the 3',5'-cyclic monophosphates of inosine, cytidine, uridine and thymidine stimulated the fluid secretion rate (FSR) of Malpighian tubules isolated from Drosophila melanogaster. The evidence suggested that the cyclic nucleotides acted intracellularly in some capacity. Receptors of the
Galen E Flynn et al.
The Journal of general physiology, 121(6), 563-582 (2003-05-29)
Cyclic nucleotide-gated (CNG) channels belong to the P-loop-containing family of ion channels that also includes KcsA, MthK, and Shaker channels. In this study, we investigated the structure and rearrangement of the CNGA1 channel pore using cysteine mutations and cysteine-specific modification.
M S Shapiro et al.
Biophysical journal, 78(5), 2307-2320 (2000-04-25)
In vertebrate olfactory receptors, cAMP produced by odorants opens cyclic nucleotide-gated (CNG) channels, which allow Ca(2+) entry and depolarization of the cell. These CNG channels are composed of alpha subunits and at least two types of beta subunits that are
R C Ganassin et al.
Journal of cellular physiology, 160(3), 409-416 (1994-09-01)
The influence of inosine on DNA synthesis by Chinook salmon embryo cells (CHSE-214) was investigated because previously cell number was shown to increase from six- to thirtyfold if inosine was added to the basal medium (L-15) supplemented with either dialyzed
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