I1786

ID-8

≥98% (HPLC)

• Sinónimos: 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol
• Fórmula empírica (notación de Hill): C₁₆H₁₄N₂O₄
• Número CAS: 147591-46-6
• Peso molecular: 298.29
• NACRES: NA.77
• PubChem Substance ID: 329815358
• UNSPSC Code: 12352200
• MDL number: MFCD00593367
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• color: yellow
• solubility: DMSO: ≥10 mg/mL
• storage temp.: 2-8°C
• SMILES string: COc1ccc(cc1)-n2c(C)c([N+]([O-])=O)c3ccc(O)cc23
• InChI: 1S/C16H14N2O4/c1-10-16(18(20)21)14-8-5-12(19)9-15(14)17(10)11-3-6-13(22-2)7-4-11/h3-9,19H,1-2H3
• InChI key: VVZNWYXIOADGSW-UHFFFAOYSA-N

Descripción

General description

ID-8 is an inhibitor of dual-specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A).

Biochem/physiol Actions

ID-8 sustains self-renewal and pluripotency of mouse embryonic stem cells (ESCs) in vitro. Stimulates proliferation at a steady rate (observed in serum-free media supplemented with 10 μM over a 30 day period).

Sustains self-renewal and pluripotency of mouse embryonic stem cells (ESCs) in vitro.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3