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H6750

Sigma-Aldrich

Hippuryl-Lys

Sinónimos:

N-Benzoyl-Gly-Lys

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About This Item

Fórmula empírica (notación de Hill):
C15H21N3O4
Número de CAS:
740-63-6
Peso molecular:
307.34
MDL number:
MFCD00038208
UNSPSC Code:
12352204
PubChem Substance ID:
24895759
NACRES:
NA.32

assay

≥98% (TLC)

form

powder

solubility

water: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

NCCCCC(NC(=O)CNC(=O)c1ccccc1)C(O)=O

InChI

1S/C15H21N3O4/c16-9-5-4-8-12(15(21)22)18-13(19)10-17-14(20)11-6-2-1-3-7-11/h1-3,6-7,12H,4-5,8-10,16H2,(H,17,20)(H,18,19)(H,21,22)

InChI key

LRCZLURYHGISRZ-UHFFFAOYSA-N

Substrates

Substrate for carboxypeptidase B and carboxypeptidase N.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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L Michelutti et al.
Clinical biochemistry, 20(1), 21-29 (1987-02-01)
Creatine kinase conversion factor has been isolated from human serum and purified to electrophoretic and chromatographic homogeneity. The enzyme sequentially converts creatine kinase MM3 to MM2 and MM1 and hydrolyzes lysine and arginine from hippuryl-L-lysine and hippuryl-L-arginine. Data on molecular
R J Edwards et al.
The Biochemical journal, 221(2), 465-470 (1984-07-15)
The effect of partially purified 'creatine kinase conversion factor' on rabbit muscle creatine kinase is shown to be that of a carboxypeptidase, removing the C-terminal lysine residue from both subunits. These changes fully explain the three-banded electrophoretic patterns of the
F Marceau et al.
Journal of chromatography, 266, 173-177 (1983-08-26)
A rapid and sensitive method for measuring carboxypeptidase N (CPN) activity in human plasma is described. The procedure is based on the hydrolysis of a high-specificity/low-affinity substrate, hippuryl-L-lysine, to its products hippuric acid and lysine. The substrate and product are
Koichi Itakura et al.
Chemistry and physics of lipids, 124(2), 81-88 (2003-06-24)
2-Hydroxyheptanal (2-HH) is one of the major aldehydes derived from peroxidation of polyunsaturated fatty acids. In the present study, to obtain an insight into the contributions of 2-HH to protein modifications during lipid peroxidation, a lysine-containing dipeptide, N(alpha)-hippuryllysine (N-benzoylglycyl-L-lysine, BGL)
Andreas Natsch et al.
Chemical research in toxicology, 23(12), 1913-1920 (2010-09-28)
(E)-4-(ethoxymethylene)-2-phenyloxazol-5(4H)-one, commonly referred to as oxazolone, is the most potent skin sensitizer in published databases as determined with the murine local lymph node assay. It has been used very widely in immunological research to induce and elicit skin sensitization reactions
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