G8048

GLP-1R agonist

≥98% (HPLC), powder, glucose homeostasis regulator

• Sinónimos: 2-Quinoxalinamine, 6,7-dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)-, 6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxaline (DMB), Compound 2
• Fórmula empírica (notación de Hill): C₁₃H₁₅Cl₂N₃O₂S
• Número CAS: 281209-71-0
• Peso molecular: 348.25
• MDL number: MFCD11521508
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Propiedades

• Nombre del producto: GLP-1R agonist, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: light brown-yellow
• solubility: DMSO: ≥10 mg/mL
• storage temp.: 2-8°C
• SMILES string: [S](=O)(=O)(C)c1nc2c(nc1NC(C)(C)C)cc(c(c2)Cl)Cl
• InChI: 1S/C13H15Cl2N3O2S/c1-13(2,3)18-11-12(21(4,19)20)17-10-6-8(15)7(14)5-9(10)16-11/h5-6H,1-4H3,(H,16,18)
• InChI key: GNZCSGYHILBXLL-UHFFFAOYSA-N

Descripción

General description

Glucagon-like peptide-1 receptor (GLP-1R) agonist is a potential oral drug for modulating glucagon-like peptide (GLP)-1 in diabetic patients. GLP-1R agonists play a key role in lowering glycated hemoglobin levels. It improves glycemic control and maintenance of body weight.

Biochem/physiol Actions

GLP-1R is a small molecule GLP-1 receptor agonist.

GLP-1R is a small molecule GLP-1 receptor agonist. GLP-1 receptor signaling is a predominant mechanism for regulating glucose homeostasis. This compound represents a unique non-peptide tool for studying the role of GLP-1 in both in vivo and in vitro diabetes and obesity models.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable