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Merck

G6503

Sigma-Aldrich

4-Guanidinobutyric acid

≥98%, for peptide synthesis

Sinónimos:

γ-Guanidinobutyric acid

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About This Item

Fórmula lineal:
NH=C(NH2)NHCH2CH2CH2COOH
Número de CAS:
Peso molecular:
145.16
Beilstein/REAXYS Number:
1766447
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.26

product name

4-Guanidinobutyric acid, ≥98%

assay

≥98%

form

powder or chunks

technique(s)

drug transporter assay: suitable

color

white

mp

280-282 °C

storage temp.

2-8°C

SMILES string

NC(=N)NCCCC(O)=O

InChI

1S/C5H11N3O2/c6-5(7)8-3-1-2-4(9)10/h1-3H2,(H,9,10)(H4,6,7,8)

InChI key

TUHVEAJXIMEOSA-UHFFFAOYSA-N

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Application

Gamma-Guanidinobutyric acid (4-GBA) is used to study intestinal transport by the human proton-coupled amino acid transporter(s) (hPAT1). 4-GBA is used with other model compounds such as 1,6-diaminohexane, 1,6-diguanidinohexane, and 1,6-di(cyanoguanidino)hexane to study the biodegradability of the biocide polyhexamethylene biguanide (PHMB).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificados de análisis (COA)

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M Al Banchaabouchi et al.
Metabolism: clinical and experimental, 47(3), 355-361 (1998-03-21)
Renal failure is characterized by the retention of nitrogenous metabolites such as urea, creatinine (CTN) and other guanidino compounds (GCs), uric acid, and hippuric acid, which could be related to the clinical syndrome associated with renal insufficiency. A model of
Guanidino compounds in hyperargininemia.
B Marescau et al.
Advances in experimental medicine and biology, 153, 427-434 (1982-01-01)
Zhipan Zhang et al.
The journal of physical chemistry. B, 109(46), 21818-21824 (2006-07-21)
Dye-sensitized solar cells based on nanocrystalline TiO(2) have been fabricated with an amphiphilic ruthenium sensitizer [Ru (4,4'-dicarboxylic acid-2,2'-bipyridine) (4,4'-bis(p-hexyloxystyryl)-2,2'-bipyridine)(NCS)(2)], coded as K-19, and 4-guanidinobutyric acid (GBA) as coadsorbent. The cells showed a approximately 50 mV increase in open-circuit voltage and
M Al Banchaabouchi et al.
Metabolism: clinical and experimental, 50(12), 1418-1425 (2001-12-06)
The long-term adverse consequences of early renal mass reduction in mice have not yet been investigated. The effects of partial surgical nephrectomy (NX) in 2-month-old mice on some biological parameters, on histopathologic and morphometric features of the kidney, and on
Disturbed metabolism of guanidino compounds characterized by elevated excretion of beta-guanidinopropionic acid and gamma-guanidinobutyric acid--an effect of vigabatrin treatment?
A Schulze et al.
Journal of inherited metabolic disease, 21(3), 268-271 (1998-08-01)

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