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Merck
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G2878

Sigma-Aldrich

Glycocholic acid hydrate

synthetic, ≥97% (HPLC)

Sinónimos:

3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide, Cholylglycine, N-(3α,7α,12α-Trihydroxy-24-oxocholan-24-yl)-glycine

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About This Item

Fórmula empírica (notación de Hill):
C26H43NO6 · xH2O
Número de CAS:
1192657-83-2
Peso molecular:
465.62 (anhydrous basis)
Beilstein/REAXYS Number:
2955826
MDL number:
MFCD06408004
UNSPSC Code:
12161900
PubChem Substance ID:
24895107
NACRES:
NA.25

biological source

synthetic

description

anionic

assay

≥97% (HPLC)

form

powder

mol wt

average mol wt 1000

aggregation number

2.1

technique(s)

enzyme immunoassay: suitable

CMC

7.1

functional group

amide

shipped in

ambient

storage temp.

room temp

SMILES string

O.C[C@H](CCC(=O)NCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI

1S/C26H43NO6.H2O/c1-14(4-7-22(31)27-13-23(32)33)17-5-6-18-24-19(12-21(30)26(17,18)3)25(2)9-8-16(28)10-15(25)11-20(24)29;/h14-21,24,28-30H,4-13H2,1-3H3,(H,27,31)(H,32,33);1H2/t14-,15+,16-,17-,18+,19+,20-,21+,24+,25+,26-;/m1./s1

InChI key

WDKPRHOCWKLQPK-ZUHYDKSRSA-N

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Application

Glycocholic acid hydrate has been used in a study to assess the invasiveness of Cryptosporidium spp. Into cultured cells. It has also been used in a study to investigate the interaction of chitosan and oil-in-water emulsions under conditions simulating the digestive system.

Biochem/physiol Actions

Bile Acid

related product

Referencia del producto
Descripción
Precios

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

Eyeshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Yazhou He et al.
PloS one, 9(3), e91202-e91202 (2014-03-14)
Association between the single nucleotide polymorphism rs3218536 (known as Arg188His) located in the X-ray repair cross complementing group 2 (XRCC2) gene and cancer susceptibility has been widely investigated. However, results thus far have remained controversial. A meta-analysis was performed to
Konstantin Kazankov et al.
Hepatology (Baltimore, Md.), 60(2), 521-530 (2014-03-14)
Macrophages are involved in inflammation and liver fibrosis and soluble (s)CD163 is a specific marker of activated macrophages. We investigated associations between sCD163 and biochemical and histological parameters of inflammatory activity and fibrosis in 551 patients with chronic hepatitis C
Raj S Bhopal et al.
The lancet. Diabetes & endocrinology, 2(3), 218-227 (2014-03-14)
The susceptibility to type 2 diabetes of people of south Asian descent is established, but there is little trial-based evidence for interventions to tackle this problem. We assessed a weight control and physical activity intervention in south Asian individuals in
Jacqueline M Major et al.
The Journal of nutrition, 144(5), 729-733 (2014-03-14)
Vitamin E (α-tocopherol) plays a key role in the regulation of cell growth and differentiation and has been studied as a potential chemopreventive agent for prostate cancer. The association of serum vitamin E concentrations with cancer risk may be modified
Emanuel Christ et al.
The lancet. Diabetes & endocrinology, 1(2), 115-122 (2014-03-14)
Small benign insulinomas are hard to localise, leading to difficulties in planning of surgical interventions. We aimed to prospectively assess the insulinoma detection rate of single-photon emission CT in combination with CT (SPECT/CT) with a glucagon-like peptide-1 receptor avid radiotracer
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