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Merck

E3127

Sigma-Aldrich

cis-11,14-Eicosadienoic acid

≥98%, liquid

Sinónimos:

11,14-Eicosadienoic acid

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About This Item

Fórmula lineal:
CH3(CH2)4(CH=CHCH2)2(CH2)8CO2H
Número de CAS:
Peso molecular:
308.50
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.25

biological source

plant

assay

≥98%

form

liquid

bp

198 °C/0.08 mmHg (lit.)

application(s)

food and beverages

functional group

carboxylic acid

lipid type

omega FAs

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCC\C=C/C\C=C/CCCCCCCCCC(O)=O

InChI

1S/C20H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10H,2-5,8,11-19H2,1H3,(H,21,22)/b7-6-,10-9-

InChI key

XSXIVVZCUAHUJO-HZJYTTRNSA-N

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Packaging

Sealed ampule.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

143.6 °F - closed cup

flash_point_c

62 °C - closed cup


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M J Steinbeck et al.
Journal of leukocyte biology, 49(4), 360-368 (1991-04-01)
To investigate NADPH-oxidase activation, we studied the effects of free fatty acid (FFA), their uncharged derivatives, and calcium on membrane lipid structure and superoxide anion (O2-) release from intact neutrophils and in cell-free O2(-)-generating systems. This study determined that in
Y Angela Liou et al.
Prostaglandins, leukotrienes, and essential fatty acids, 80(4), 201-206 (2009-04-10)
High intakes of linoleic acid (LA,18:2n-6) have raised concern due to possible increase in arachidonic acid (ARA, 20:4n-6) synthesis, and inhibition of alpha linolenic acid (ALA, 18:3n-3) desaturation to eicosapentaenoic (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3). In healthy men
Samia Selmi-Ruby et al.
Environmental health perspectives, 128(12), 127006-127006 (2020-12-10)
Aryl phosphate esters (APEs) are widely used and commonly present in the environment. Health hazards associated with these compounds remain largely unknown and the effects of diphenyl phosphate (DPhP), one of their most frequent derivatives, are poorly characterized. Our aim
Yung-Sheng Huang et al.
Molecular and cellular biochemistry, 358(1-2), 85-94 (2011-06-21)
Eicosadienoic acid (Δ11,14-20:2; EDA) is a rare, naturally occurring n-6 polyunsaturated fatty acid (PUFA) found mainly in animal tissues. EDA is elongated from linoleic acid (LA), and can also be metabolized to dihomo-γ-linolenic acid (DGLA), arachidonic acid (AA), and sciadonic
R Mogul et al.
Biochemistry, 40(14), 4391-4397 (2001-04-04)
Lipoxygenases are currently potential targets for therapies against asthma, artherosceloris, and cancer. Recently, inhibition studies on both soybean (SLO) and human lipoxygenase (15-HLO) revealed the presence of an allosteric site that binds both substrate, linoleic acid, and inhibitors; oleic acid

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