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E1132

17β-Estradiol

ER agonist

Sinónimos:

1,3,5-Estratriene-3,17β-diol, 17β-Estradiol, 3,17β-Dihydroxy-1,3,5(10)-estratriene, Dihydrofolliculin

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Acerca de este artículo

Fórmula empírica (notación de Hill):
C18H24O2
Número CAS:
Peso molecular:
272.38
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352104
EC Number:
200-023-8
MDL number:
Beilstein/REAXYS Number:
1914275
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Nombre del producto

β-Estradiol, analytical standard

grade

analytical standard

Quality Segment

packaging

vial of 250 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

176-180 °C (lit.)

application(s)

pharmaceutical

SMILES string

O[C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(O)=CC=C4[C@@]3([H])CC[C@@]21C

InChI

1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1

InChI key

VOXZDWNPVJITMN-ZBRFXRBCSA-N

Biochem/physiol Actions

The major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation. Exposure to estradiol increases breast cancer incidence and proliferation.
The major estrogen secreted by the premenopausal ovary.

Packaging

Supplied in amber screw-cap vials

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Este artículo
E2758PHR1353PHR1353
Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

300

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

cell culture | mammalian: suitable, single cell analysis: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

176-180 °C (lit.)

mp

176-180 °C (lit.)

mp

176-180 °C (lit.)

mp

176-180 °C (lit.)

packaging

vial of 250 mg

packaging

-

packaging

-

packaging

-

application(s)

pharmaceutical

application(s)

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

grade

analytical standard

grade

-

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard


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pictograms

Health hazardEnvironment

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 1A

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges



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Certificados de análisis (COA)

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Questions

  1. Can I just confirm that this product is water soluble, please? Thank you.

    1 answer
    1. The solubility of this product in water has not been determined. However, various sources report a solubility rate of 3.6 - 3.9 mg/L in water. Please see the link below to review these sources from PubChem:
      https://pubchem.ncbi.nlm.nih.gov/compound/Estradiol#section=Solubility

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