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E0789

Casein, Hammarsten bovine

Sinónimos:

Casein from bovine milk

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Número CAS:
UNSPSC Code:
12352202
NACRES:
NA.61
EC Number:
232-555-1
MDL number:
Form:
powder
Assay:
>90% dry basis
Biological source:
bovine milk (Hammarsten)
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biological source

bovine milk (Hammarsten)

Quality Segment

assay

>90% dry basis

form

powder

technique(s)

enzyme immunoassay: suitable

mp

280 °C (dec.) (lit.)

UniProt accession no.

storage temp.

room temp

SMILES string

[P](=O)(OCC(NC(=O)C(NC(=O)C(N)Cc1ccccc1)CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(C(O)C)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(C

InChI

1S/C81H125N22O39P/c1-36(2)31-50(76(132)94-43(15-24-57(87)108)71(127)101-52(34-64(120)121)78(134)98-49(81(137)138)11-7-8-30-82)99-72(128)47(19-28-61(114)115)95-77(133)51(33-63(118)119)100-73(129)48(20-29-62(116)117)97-80(136)65(37(3)104)103-75(131)44(16-25-58(88)109)92-68(124)42(14-23-56(86)107)90-67(123)41(13-22-55(85)106)91-69(125)45(17-26-59(110)111)93-70(126)46(18-27-60(112)113)96-79(135)53(35-142-143(139,140)141)102-74(130)40(12-21-54(84)105)89-66(122)39(83)32-38-9-5-4-6-10-38/h4-6,9-10,36-37,39-53,65,104H,7-8,11-35,82-83H2,1-3H3,(H2,84,105)(H2,85,106)(H2,86,107)(H2,87,108)(H2,88,109)(H,89,122)(H,90,123)(H,91,125)(H,92,124)(H,93,126)(H,94,132)(H,95,133)(H,96,135)(H,97,136)(H,98,134)(H,99,128)(H,100,129)(H,101,127)(H,102,130)(H,103,131)(H,110,111)(H,112,113)(H,114,115)(H,116,117)(H,118,119)(H,120,121)(H,137,138)(H2,139,140,141)

InChI key

BECPQYXYKAMYBN-UHFFFAOYSA-N

General description

Casein is an amphiphilic protein.
Casein, a phosphoprotein, is the principal protein component of milk which is almost entirely expressed in the lactating mammary gland.[1] In bovine milk they are classified according to their calcium sensitivity: αs1-, αs2-, and β-caseins precipitate in the presence of calcium; whereas κ-casein remains in solution. [2]

Application

Casein, Hammarsten bovine has been used as a substrate for Aplysia californica calpain to study its activity.[3]
The product is useful as a protease substrate.

Biochem/physiol Actions

Casein is useful in food industries and non-food applications. It has the property for emulsification, foam formation, and stabilization, water-binding, and gelation. Casein is also considered heat and acid-stable.
Partial gastrointestinal digestion of casein is a rich source of bioactive peptides, such as β-casomorphin. However, bovine casein is not homogeneous; variants A1 and B do lead to production of β-casomorphin 7 production, while A2 does not.

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Este artículo
C4765C6905C0406
biological source

bovine milk (Hammarsten)

biological source

bovine milk

biological source

bovine milk

biological source

bovine milk

assay

>90% dry basis

assay

-

assay

≥98% (PAGE)

assay

≥70% (PAGE)

technique(s)

enzyme immunoassay: suitable

technique(s)

activity assay: suitable, electrophoresis: suitable, immunocytochemistry: suitable

technique(s)

activity assay: suitable

technique(s)

isoelectric focusing (IEF): suitable

form

powder

form

liquid

form

essentially salt-free, lyophilized powder

form

lyophilized powder

storage temp.

room temp

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

Gene Information

bovine ... CSN1S1(282208), CSN1S2(282209), CSN2(281099), CSN3(281728)

Gene Information

bovine ... CSN1S1(282208), CSN1S2(282209), CSN2(281099), CSN3(281728)

Gene Information

bovine ... CSN2(281099), CSN3(281728)

Gene Information

cow ... MKCAS(100531419), MKCASP(105755569)


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Clase de almacenamiento

11 - Combustible Solids



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Questions

  1. 製薬会社で医薬品の品質試験を行なっている者です。このカゼイン(Hammerstein)において、日局等の公定書に基づいて赤外吸収スペクトル測定法の臭化カリウム錠剤法の試験を実施した実績がありますでしょうか。もしなければ、実施実績のある他のカゼイン(Hammerstein)製品の取扱いはございますでしょうか。ご回答お願いいたします。

    1 answer
    1. There are currently two Hammerstein versions of Casein available, E0789 and 1.02242. Neither of these products are tested according to the JP.

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