D2531

Dextromethorphan hydrobromide monohydrate

≥99% (TLC)

• Sinónimos: d-3-Methoxy-N-methylmorphinan hydrobromide monohydrate, (9S,13S,14S)-3-Methoxy-17-methylmorphinan hydrobromide
• Fórmula empírica (notación de Hill): C₁₈H₂₅NO · HBr · H₂O
• Número CAS: 6700-34-1
• Peso molecular: 370.32
• UNSPSC Code: 12352200
• NACRES: NA.77
• PubChem Substance ID: 57654086
• MDL number: MFCD02173901
• Beilstein/REAXYS Number: 6453793
• Assay: ≥99% (TLC)
• Form: powder

Propiedades

• Quality Segment: 200
• description: Kábítószer / Narcotic Drug (Hungary), 78/2022. (XII. 28.) BM rendelet
• assay: ≥99% (TLC)
• form: powder
• SMILES string: Br[H].[H]O[H].[H][C@]12CCCC[C@]13CCN(C)[C@H]2Cc4ccc(OC)cc34
• InChI: 1S/C18H25NO.BrH.H2O/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H;1H2/t15-,17+,18+;;/m1../s1
• InChI key: STTADZBLEUMJRG-IKNOHUQMSA-N
• Gene Information: human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRIN3A(116443), GRIN3B(116444), SIGMAR1(10280)

Descripción

Application

Dextromethorphan hydrobromide monohydrate has been used as a substrate for cytochrome P450 2D6 enzyme action, in potassium phosphate buffer for measuring P450 activity and is used in enzyme inhibition studies.

Biochem/physiol Actions

Dextromethorphan hydrobromide is an allosteric antagonist at N-methyl D- aspartate (NMDA)-controlled ion channels and antagonist at voltage-dependent channels. Dextromethorphan hydrobromide is useful in treating dry cough.

Información de seguridad

• Pictogramas: GHS06,GHS09
• Palabra de advertencia: Danger
• Códigos de peligro: H301,H411
• Indicaciones de precaución: P264 - P270 - P273 - P301 + P310 - P391 - P405
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 2
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• ¿Qué está pasando?: WGK 2
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• EPI (equipos de protección individual): Eyeshields, Gloves, type N95 (US)