C7632

Cantharidin

protein phosphatase 2 A (PPA2) inhibitor

• Sinónimos: 3a,7a-Dimethylhexahydro-4,7-epoxyisobenzofuran-1,3-dione, 7a-Dimethylhexahydro-3a,4,7-epoxyisobenzofuran, Cantharidine, Hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione
• Fórmula empírica (notación de Hill): C₁₀H₁₂O₄
• Número CAS: 56-25-7
• Peso molecular: 196.20
• NACRES: NA.77
• PubChem Substance ID: 24278334
• UNSPSC Code: 12352200
• EC Number: 200-263-3
• MDL number: MFCD00134968

Propiedades

• Nombre del producto: Cantharidin,
• Quality Segment: 200
• color: white
• mp: 215-217 °C (lit.), 215-218 °C
• solubility: DMSO: soluble, ethanol: soluble
• SMILES string: C[C@]12C3CCC(O3)[C@@]1(C)C(=O)OC2=O
• InChI: 1S/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3/t5-,6+,9+,10-
• InChI key: DHZBEENLJMYSHQ-XCVPVQRUSA-N
• Gene Information: human ... PPP2CA(5515), PPP2CB(5516), PPP2CBP(5517), PPP2R1A(5518), PPP2R1B(5519), PPP2R2A(5520), PPP2R2B(5521), PPP2R2C(5522), PPP2R3A(5523), PPP2R5A(5525)

Descripción

General description

Cantharidin is a poisonous vesicant, which is produced by blister bees. It is used to treat piles, ulcers, venomous worms and tuberculous scrofuloderma. It is used as an aphrodisiac, abortifacient and a veterinary medicine diuretic.

Application

Cantharidin has been used to inhibit protein phosphatase 2 (PP2A).

Biochem/physiol Actions

Inhibitor of protein phosphatase 2A.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Información de seguridad

• pictograms: GHS06
• signalword: Danger
• hcodes: H300,H315,H319,H335
• pcodes: P261 - P264 - P271 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Clase de almacenamiento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges