C6240

CITCO

≥98% (HPLC), androstane receptor agonist, solid

• Sinónimos: 6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime
• Fórmula empírica (notación de Hill): C₁₉H₁₂N₃OCl₃S
• Número CAS: 338404-52-7
• Peso molecular: 436.74
• UNSPSC Code: 12352203
• PubChem Substance ID: 24724448
• NACRES: NA.77
• MDL number: MFCD00139608
• Assay: ≥98% (HPLC)
• Form: solid
• Storage condition: desiccated

Propiedades

• Nombre del producto: CITCO, ≥98% (HPLC), solid
• assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated
• solubility: DMSO: soluble 28 mg/mL, H₂O: insoluble
• storage temp.: −20°C
• SMILES string: Clc1ccc(cc1)-c2nc3sccn3c2\C=N\OCc4ccc(Cl)c(Cl)c4
• InChI: 1S/C19H12Cl3N3OS/c20-14-4-2-13(3-5-14)18-17(25-7-8-27-19(25)24-18)10-23-26-11-12-1-6-15(21)16(22)9-12/h1-10H,11H2/b23-10+
• InChI key: ZQWBOKJVVYNKTL-AUEPDCJTSA-N

Descripción

General description

CITCO is an imidazothiazole derivative. It stimulates human constitutive androstane receptor (CAR) nuclear translocation.

Application

CITCO has been used for the activation of mouse constitutive androstane receptor (CAR) and human CAR.

Biochem/physiol Actions

CITCO is a constitutive androstane receptor (CAR) agonist; nuclear receptor NR113 agonist.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves