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Merck

C2105

Sigma-Aldrich

Z-Val-Ala-Asp fluoromethyl ketone

powder, ≥90% (TLC)

Sinónimos:

Z-VAD-FMK, Non-methylated

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About This Item

Fórmula empírica (notación de Hill):
C21H28FN3O7
Número de CAS:
Peso molecular:
453.46
Número MDL:
Código UNSPSC:
12352209
ID de la sustancia en PubChem:
NACRES:
NA.77

Nivel de calidad

Ensayo

≥90% (TLC)

Formulario

powder

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)CF

InChI

1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1

Clave InChI

SUUHZYLYARUNIA-YEWWUXTCSA-N

Categorías relacionadas

Amino Acid Sequence

Z-Val-Ala-Asp-OMe-FMK

Acciones bioquímicas o fisiológicas

Non-methylated competitive and irreversible inhibitor of caspase-1, as well as other caspases, which can be used directly with purified enzymes. It does not require esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(OMe) fluoromethyl ketone (Product Code V-116).

Características y beneficios

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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