A9013
1,5-Bis(4-allyldimethylammoniumphenyl)pentan-3-one dibromide
≥97% (HPLC), acetylcholinesterase inhibitor, powder
Sinónimos:
BW 284c51
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Fórmula lineal:
C27H38N2OBr2
Número CAS:
Peso molecular:
566.41
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
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Servicio técnico
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Permítanos ayudarleNombre del producto
1,5-Bis(4-allyldimethylammoniumphenyl)pentan-3-one dibromide,
assay
≥97% (HPLC)
Quality Level
form
powder
solubility
water: 19.60-20.40 mg/mL, clear, colorless
storage temp.
room temp
SMILES string
Br.C[N](C)(CC=C)c1ccc(CCC(=O)CCc2ccc(cc2)[N](C)(C)CC=C)cc1
InChI
1S/C27H38N2O.BrH/c1-7-21-28(3,4)25-15-9-23(10-16-25)13-19-27(30)20-14-24-11-17-26(18-12-24)29(5,6)22-8-2;/h7-12,15-18H,1-2,13-14,19-22H2,3-6H3;1H
InChI key
XBXRQUYORADPMX-UHFFFAOYSA-N
Gene Information
human ... ACHE(43)
Biochem/physiol Actions
Selective acetylcholinesterase inhibitor.
Features and Benefits
This compound is featured on the Acetylcholine Synthesis and Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral
Clase de almacenamiento
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Silvia Olivera-Bravo et al.
British journal of pharmacology, 144(1), 88-97 (2005-01-13)
This work was aimed to determine if 1,5-bis(4-allyldimethylammoniumphenyl)pentan-3-one dibromide (BW284c51), the most selective acetylcholinesterase inhibitor (AchEI), affects the nicotinic acetylcholine (Ach) receptor (AchR) function. Purified Torpedo nicotinic AchRs were injected into Xenopus laevis oocytes and BW284c51 effects on Ach- and
Kevin B Temeyer et al.
Veterinary parasitology, 172(1-2), 114-121 (2010-05-11)
Rhipicephalus (Boophilus) microplus cDNAs, BmAChE1, BmAChE2, and BmAChE3, were previously identified as presumptively encoding acetylcholinesterases (AChEs), but biochemical identity was confirmed only for recombinant BmAChE3. In the present study, four recombinant BmAChE1 constructs and single recombinant constructs of BmAChE2 and
Marcia D Howard et al.
Toxicology, 238(2-3), 157-165 (2007-07-24)
Organophosphorus (OP) pesticides elicit acute toxicity by inhibiting acetylcholinesterase (AChE), the enzyme responsible for inactivating acetylcholine (ACh) at cholinergic synapses. A number of OP toxicants have also been reported to interact directly with muscarinic receptors, in particular the M(2) muscarinic
Número de artículo de comercio global
| SKU | GTIN |
|---|---|
| A9013-25MG | 04061833401170 |
| A9013-100MG | 04061833401163 |
| A9013-250MG | 04061832945316 |