Amlodipine besylate is not a narcotic substance. It is a L-type calcium channel blocker typically used to treat angina and hypertension. Note that unless otherwise stated this product is intended for research use only and is not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
A5605
Amlodipine besylate
≥98% (HPLC), L-type calcium channel blocker, powder
Sinónimos:
2-[(2-Aminoethoxy)-methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5- pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzene sulfonate, Norvasc
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Acerca de este artículo
Fórmula empírica (notación de Hill):
C20H25ClN2O5 · C6H5SO3H
Número CAS:
Peso molecular:
567.05
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
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Servicio técnico
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Permítanos ayudarleNombre del producto
Amlodipine besylate, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white
solubility
DMSO: ≥20 mg/mL
SMILES string
OS(=O)(=O)c1ccccc1.CCOC(=O)C2=C(COCCN)NC(C)=C(C2c3ccccc3Cl)C(=O)OC
InChI
1S/C20H25ClN2O5.C6H6O3S/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;7-10(8,9)6-4-2-1-3-5-6/h5-8,17,23H,4,9-11,22H2,1-3H3;1-5H,(H,7,8,9)
InChI key
ZPBWCRDSRKPIDG-UHFFFAOYSA-N
Gene Information
human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779)
Application
Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats.
Biochem/physiol Actions
Amlodipine besylate is an L-type calcium channel blocker.
Amlodipine is an L-type calcium channel blocker. Amlodipine belongs to a class of cardiovascular drugs, which act at the voltage gated calcium channel of the CaV1, or L-type, class. Amlodipine also has antihypertensive and antianginal effects. Its activity resides mainly in the (-)-isomer. Amlodipine inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats.
Features and Benefits
This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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Este artículo | |||
|---|---|---|---|
| description ≥98% (HPLC) | description Pharmaceutical Secondary Standard; Certified Reference Material | description European Pharmacopoeia (EP) Reference Standard | description ≥98% (HPLC) |
| assay ≥98% (HPLC) | assay - | assay - | assay ≥98% (HPLC) |
| form powder | form - | form - | form powder |
| Quality Level 100 | Quality Level 300 | Quality Level - | Quality Level - |
| solubility DMSO: ≥20 mg/mL | solubility - | solubility - | solubility DMSO: 2 mg/mL, clear |
| color white | color - | color - | color white to beige |
| Gene Information human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779) | Gene Information human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779) | Gene Information human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779) | Gene Information - |
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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