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Merck

68795

Hydrophobin SC3

≥98% (SDS-GE)

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NACRES:
NA.61
UNSPSC Code:
12352202
Form:
solid
Assay:
≥98% (SDS-GE)
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Quality Segment

assay

≥98% (SDS-GE)

form

solid

UniProt accession no.

storage temp.

−20°C

Gene Information

Schizophyllum commune H4-8 ... SC3(9592530)

General description

Hydrophobin SC3 is a class I hydrophobin of Schizophyllum commune. It is an oligomeric amphiphilic protein, rich in β-sheet. The mature protein consists of four disulfide bridges comprising eight cysteine residues. The N-terminal contains mannose residues in combination with threonine residues.

Application

Hydrophobin SC3 has been used to coat nitric oxide (NO) releasing medical-grade polymer to establish an antifouling layer to work synergistically with NO′s bactericidal and antiplatelet activity (SC3-NO).

Biochem/physiol Actions

Hydrophobins are key regulators of fungal growth and development. The hydrophobin SC3 is known for its ability to assemble at the water and air, water and oil, and water and a hydrophobic solid interface. The self-assembling process subjects hydrophobin SC3 to many conformational changes. It permits the growth of aerial hyphae and fruiting bodies on fungi as a result of assembling at the water-air interface. Hydrophobin SC3 mediates the linking of cell wall glucans to chitin and helps in the hyphal cell wall formation. Hydrophobin SC3 might have antitumor actions and be useful in chemotherapy and radiation.

Other Notes

Currently available only in Europe.


Clase de almacenamiento

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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