Mito Red is a cell membrane permeable rhodamine based dye. It localizes mitochondria, and emits red fluorescence. The interaction of Mito Red with mitochondria depends of the membrane potential of the mitochondria. Mitochondria can be stained with 20-200 nM of Mito Red.
application
MitoRed (Mito Red), a vital dye and mitochondrial stain, is used to indicate the status of mitochondria under various physiological and physical conditions.
We investigated the mitochondrial behavior, localization and heteroplasmy in reconstituted oocytes derived from germinal vesicle (GV) transfers. The karyoplast containing the GV nucleus and the ooplast (enucleated oocyte) were prepared from GV oocytes derived from B6D2F1 mice. Mitochondria in the
The Journal of cell biology, 188(1), 101-114 (2010-01-13)
Macroautophagy is a catabolic pathway used for the turnover of long-lived proteins and organelles in eukaryotic cells. The morphological hallmark of this process is the formation of double-membrane autophagosomes that sequester cytoplasm. Autophagosome formation is the most complex part of
We report a novel green-fluorescent NO donor, NBDNO, bearing a 2,6-dimethylnitrobenzene moiety for photocontrollable NO release and a triphenylphosphonium moiety for targeting to mitochondria. Photorelease of NO from NBDNO was confirmed by means of ESR analysis in aqueous solution. Intracellular
Antimicrobial agents and chemotherapy, 56(11), 5982-5985 (2012-08-02)
Many successful antimicrobial drugs originate from synthetic dyes. This paper reports the in vitro activity of 14 fluorescent dyes against Plasmodium falciparum. Five of these dyes (Hoechst 33342, MitoRed, DiOC(6), SYTO 9, and rhodamine B) show activity at a low
Journal of biomedicine & biotechnology, 2010, 147835-147835 (2010-05-22)
Alzheimer's disease (AD) and type 2 diabetes are connected in a way that is still not completely understood, but insulin resistance has been implicated as a risk factor for developing AD. Here we show an evidence that insulin is capable
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
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