07039

(R)-(+)-α-Lipoic acid

≥98.0% (HPLC)

• Sinónimos: (R)-(+)-1,2-Dithiolane-3-pentanoic acid, (R)-6,8-Dithiooctanoic acid, (R)-6,8-Thioctic acid
• Fórmula empírica (notación de Hill): C₈H₁₄O₂S₂
• Número CAS: 1200-22-2
• Peso molecular: 206.33
• UNSPSC Code: 12352202
• PubChem Substance ID: 329748332
• NACRES: NA.32
• MDL number: MFCD01631142

Propiedades

• Quality Segment: 100
• assay: ≥98.0% (HPLC)
• optical purity: enantiomeric excess: ≥98.0% (HPLC)
• mp: 48-52 °C (lit.)
• storage temp.: −20°C
• InChI: 1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1
• InChI key: AGBQKNBQESQNJD-SSDOTTSWSA-N

Descripción

Biochem/physiol Actions

(R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes. It is a biological antioxidant with prooxidant activities, its therapeutic potential is widely investigated, e.g. in the treatment for Alzheimer′s disease.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Analysis Note

identity confirmed by LC-MS

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3