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Merck

319961

Sigma-Aldrich

Carbon tetrachloride

reagent grade, 99.9%

Sinónimos:

Tetrachloromethane

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About This Item

Fórmula empírica (notación de Hill):
CCl4
Número de CAS:
Peso molecular:
153.82
Beilstein/REAXYS Number:
1098295
EC Number:
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.21

grade

reagent grade

Quality Level

vapor density

5.32 (vs air)

vapor pressure

143 mmHg ( 30 °C)
91 mmHg ( 20 °C)

assay

99.9%

form

liquid

refractive index

n20/D 1.460 (lit.)

bp

76-77 °C (lit.)

mp

−23 °C (lit.)

density

1.594 g/mL at 25 °C (lit.)

SMILES string

ClC(Cl)(Cl)Cl

InChI

1S/CCl4/c2-1(3,4)5

InChI key

VZGDMQKNWNREIO-UHFFFAOYSA-N

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General description

Carbon tetrachloride (CCl4) is a volatile and stable chlorinated hydrocarbon. It is widely used as a chemical intermediate, solvent, and dry-cleaning agent.

Application

Carbon tetrachloride can be used as:      
  • A precursor to synthesize high-surface-area mesoporous carbon material by a self-templating method in the presence of sodium-potassium alloy (NaK) as a reducing agent.      
  • A reactant to synthesize 1,2-disubstituted cyclopentanes via Cu-catalyzed ring-closing Kharasch addition reaction with 1,6-dienes.      
  • A solvent as well as a reactant to prepare diphenyl carbonate from phenol and carbon dioxide in the presence of ZnCl2 as a catalyst.

Please view www.aldrich.com/epaods regarding the EPA′s request for application information of Ozone Depleting Substances

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 2 - Ozone 1 - Skin Sens. 1B - STOT RE 1 Inhalation

target_organs

Liver,Kidney

Storage Class

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Seham S El-Din El-Hawary et al.
Antioxidants (Basel, Switzerland), 8(12) (2019-12-19)
The prevalence of hepatic diseases globally and in Egypt particularly necessitates an intensive search for natural hepatoprotective candidates. Despite the traditional use of Chrysophyllum oliviforme L. and C. cainito L. leaves in the treatment of certain ailments, evidence-based reports on
Ruihua Ma et al.
eLife, 9 (2020-03-11)
The distribution of complementary metabolic functions in hepatocytes along a portocentral axis is called liver zonation. Endothelial secreted Wnt ligands maintain metabolic zonation in the adult murine liver but whether those ligands are necessary to initiate zonation in the immature
Meritxell Huch et al.
Nature, 494(7436), 247-250 (2013-01-29)
The Wnt target gene Lgr5 (leucine-rich-repeat-containing G-protein-coupled receptor 5) marks actively dividing stem cells in Wnt-driven, self-renewing tissues such as small intestine and colon, stomach and hair follicles. A three-dimensional culture system allows long-term clonal expansion of single Lgr5(+) stem
Samar Basu
Toxicology, 189(1-2), 113-127 (2003-06-25)
Hepatic injury through carbon tetrachloride (CCl(4)) induced lipid peroxidation is well known and has been extensively used in the experimental models to understand the cellular mechanisms behind oxidative damage and further to evaluate the therapeutic potential of drugs and dietary
Mark A Barnes et al.
Journal of leukocyte biology, 97(1), 161-169 (2014-11-16)
Recruitment of peripheral monocytes to the liver is a key contributor to the response to injury. MIF can act as a chemokine and cytokine, regulating innate immune responses in many tissues and cell types. We hypothesized that MIF contributes to

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