PHR2438

Chloroquine Related Compound A

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: 4,7-Dichloroquinoline
• Fórmula empírica (notación de Hill): C₉H₅Cl₂N
• Número de CAS: 86-98-6
• Peso molecular: 198.05
• Beilstein/REAXYS Number: 125359
• MDL number: MFCD00006774
• UNSPSC Code: 41116107
• NACRES: NA.24

Propiedades

• biological source: synthetic
• Quality Level: 300
• grade: certified reference material; pharmaceutical secondary standard
• agency: BP; EP; USP; traceable to USP 1118328
• vapor pressure: 0.0000811 kPa ( 25 °C)
• API family: chloroquine
• form: crystalline
• packaging: pkg of 50 mg
• color: white to brown
• pH: 3.86 (24.9 °C)
• bp: 298.4 °F (148°C)
• mp: 81-83 °C (lit.)
• solubility: water: slightly soluble 0.037 g/L at 25 °C; ethanol: freely soluble; ether: freely soluble
• density: 1.31 g/cm³ at 20 °C (971.4 hPa)
• application(s): pharmaceutical
• storage temp.: 2-30°C
• SMILES string: Clc1ccc2c(Cl)ccnc2c1
• InChI: 1S/C9H5Cl2N/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-5H
• InChI key: HXEWMTXDBOQQKO-UHFFFAOYSA-N

Descripción

General description

Chloroquine Related Compound A is an impurity of chloroquine, a 9-aminoquinoline drug that effectively inhibits viral infections in humans.

Chloroquine Related Compound A is an impurity of chloroquine, which is a 9-aminoquinoline drug that effectively inhibits viral infections in humans.

Application

Chloroquine Related Compound A can be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography (LC) technique.

Chloroquine Related Compound A can be used as a pharmaceutical secondary standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography (LC) technique.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC4608 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Información de seguridad

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H315,H317,H319,H411
• pcodes: P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable