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Merck

PHR1229

Supelco

Ethylbenzene

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

Ethylbenzene, NSC 406903, Phenylethane

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About This Item

Fórmula lineal:
C6H5C2H5
Número de CAS:
Peso molecular:
106.17
Beilstein/REAXYS Number:
1901871
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

agency

traceable to USP 1265457

vapor density

3.7 (vs air)

vapor pressure

10 mmHg ( 20 °C)
19 mmHg ( 37.7 °C)

CofA

current certificate can be downloaded

autoignition temp.

810 °F

expl. lim.

6.7 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.495 (lit.)

bp

136 °C (lit.)

mp

−95 °C (lit.)

density

0.867 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

CCc1ccccc1

InChI

1S/C8H10/c1-2-8-6-4-3-5-7-8/h3-7H,2H2,1H3

InChI key

YNQLUTRBYVCPMQ-UHFFFAOYSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards..

Application

Ethylbenzene may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC3557 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - STOT RE 2

target_organs

hearing organs

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

71.6 °F - closed cup

flash_point_c

22.0 °C - closed cup


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Neurotoxicology, 31(3), 247-258 (2010-02-23)
The potential for neurotoxicological and immunotoxicological effects of ethylbenzene was studied in young adult Crl:CD(SD) rats following 90-day oral (neurotoxicity) or 28-day inhalation (immunotoxicity) exposures. In the neurotoxicity study, ethylbenzene was administered orally via gavage twice daily at 0, 25
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