PHR1153

Triethyl citrate

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: Ethyl citrate
• Fórmula lineal: HOC(COOC₂H₅)(CH₂COOC₂H₅)₂
• Número de CAS: 77-93-0
• Peso molecular: 276.28
• Beilstein/REAXYS Number: 1801199
• EC Number: 201-070-7
• MDL number: MFCD00009201
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823171
• NACRES: NA.24

Propiedades

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to USP 1683606
• vapor density: 9.7 (vs air)
• vapor pressure: 1 mmHg ( 107 °C)
• API family: triethyl citrate
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• refractive index: n20/D 1.442 (lit.)
• bp: 235 °C/150 mmHg (lit.)
• density: 1.14 g/mL at 25 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• SMILES string: CCOC(=O)CC(O)(CC(=O)OCC)C(=O)OCC
• InChI: 1S/C12H20O7/c1-4-17-9(13)7-12(16,11(15)19-6-3)8-10(14)18-5-2/h16H,4-8H2,1-3H3
• InChI key: DOOTYTYQINUNNV-UHFFFAOYSA-N

Descripción

General description

Triethyl citrate is an ester of citric acid and is commonly used as a plasticizer in pharmaceutical coatings including tablets, capsules, beads and granules for masking taste. It is also used as a flavoring agent in food.

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Triethyl citrate can be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Values of analytes vary lot to lot.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA8988 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

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Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: 311.0 °F - closed cup
• flash_point_c: 155 °C - closed cup