P1754

TWEEN^® 80

viscous liquid

• Sinónimos: Monooleato de POE (20) sorbitano, Monooleato de polietilenglicol sorbitano, Monooleato de polioxietilen sorbitano, Polisorbato 80
• Número de CAS: 9005-65-6
• Número MDL: MFCD00082107
• Código UNSPSC: 12161900
• NACRES: NA.21

Propiedades

• origen biológico: Porcine (tallow); bovine (tallow)
• Nivel de calidad: 200
• descripción: non-ionic
• Formulario: viscous liquid
• mol peso: micellar avg mol wt 79,000; average mol wt 1310
• composición: Oleic acid, ≥58.0% (balance primarily linoleic, palmitic, and stearic acids)
• número de agregación: 60
• CMC: 0.012 mM (20-25°C)
• viscosidad: 400-620 mPa.s
• temperatura de transición: cloud point 65 °C
• solubilidad: water: soluble, clear to slightly hazy, colorless to yellow
• densidad: 1.064 g/cm³
• HLB: 15
• aplicaciones: cell analysis
• cadena SMILES: CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO
• InChI: 1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+
• Clave InChI: RGPBUVUVZKQNHD-MDZDMXLPSA-N

Descripción

Descripción general

Tween^® 80 is a non-ionic detergent and surfactant, classified as an ester of sorbitan and oleic acid. It is a versatile compound commonly employed in various biological applications, including cell lysis, nuclei isolation, and cell fractionation. Additionally, Tween 80 finds use in stabilizing proteins and facilitating protein membrane studies. Its effectiveness stems from its membership in the polysorbate group, characterized by the combination of sorbitol and sorbitane oleic esters with polyethylene glycol chains. These structural features contribute to Tween 80′s emulsifying capabilities and a broad range of applications.

Aplicación

Non-ionic detergent used for selective protein extraction and isolation of nuclei from mammalian cell lines.

TWEEN^® 80 has been used in drug vehicle solution for specific injections in mice and rats. It has been used for the determination of esterase activity in bacterial cells.

Acciones bioquímicas o fisiológicas

TWEEN^® 80 is a polysorbate surfactant which helps in stabilizing proteins and in protein membrane studies. It is regularly used for the extraction of membrane proteins and isolation of nuclei from cells.

Características y beneficios

• Excellent wetting and dispersing agent
• Highly versatile surfactant for your Cell Biology and Biochemical research

Otras notas

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Información legal

TWEEN is a registered trademark of Croda International PLC

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): >235.4 °F - closed cup
• Punto de inflamabilidad (°C): > 113 °C - closed cup
• Equipo de protección personal: Eyeshields, Gloves