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D4911

Sigma-Aldrich

Dextran sulfate sodium salt from Leuconostoc spp.

mol wt 6,500-10,000

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About This Item

Número de CAS:
9011-18-1
Número MDL:
MFCD00081551
Código UNSPSC:
12352201
NACRES:
NA.21

origen biológico

bacterial (Leuconostoc)

Nivel de calidad

100

Formulario

powder

mol peso

6,500-10,000

composición

Sulfur Content, 16.0-22.0%

color

white to light yellow

intervalo de pH útil

6.0-8 (10 g/L)

solubilidad

H2O: 100 mg/mL

temp. de almacenamiento

room temp

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Descripción general

Dextran sulfate is a sulfated polysaccharide, which is negatively charged. It is produced by the esterification of dextran with chlorosulphonic acid. Dextran is used to treat hemorrhage, burns, surgery and trauma. It improves blood flow and prevents erythrocyte aggregation. Dextran lowers the risk of thrombosis and postoperative pulmonary emboli. It is a ribonuclease inhibitor. Dextran sulfate exhibits antiviral, anticoagulant and adjuvant properties.

Aplicación

Dextran sulfate sodium salt Leuconostoc spp has been used:
  • as a standard to perform polyacrylamide-gel electrophoresis for carbohydrates (C-PAGE)(59) and agarose gel electrophoresis(60)
  • for RNA sequential probing of targets (SPOTs) imaging(61)
  • as a component of 1% injection buffer(62)

Otras notas

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000323978
MKCW1248
MKCW7350
0000323978
MKCV2395

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Parisa Yousefpour et al.
International journal of nanomedicine, 6, 1487-1496 (2011-07-29)
This study deals with the preparation and investigation of a nanoscale delivery system for the anticancer drug doxorubicin (DOX) using its complexation with polyanionic carbohydrate dextran sulfate (DS). Dynamic light scattering, SEM, and zeta potential determination were used to characterize
Radiotherapy, Surgery, and Immunotherapy (2012)
Rheology of Industrial Polysaccharides: Theory and Applications (2012)
Radiotherapy, Surgery, and Immunotherapy (2012)
Valter R M Lombardi et al.
Journal of biomedicine & biotechnology, 2012, 826178-826178 (2012-05-24)
One of the main treatments currently used in humans to fight cancer is chemotherapy. A huge number of compounds with antitumor activity are present in nature, and many of their derivatives are produced by microorganisms. However, the search for new
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Protocolos

Dextran Sulfate

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Dextran Sulfate

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Dextran Sulfate

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Dextran Sulfate

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Contenido relacionado

Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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