60063

Potassium antimonyl tartrate trihydrate

99.0-103% (RT), purum p.a.

• Sinónimos: Antimony potassium tartrate trihydrate, Tartar emetic
• Fórmula empírica (notación de Hill): C₈H₄K₂O₁₂Sb₂ · 3H₂O
• Número CAS: 28300-74-5
• Peso molecular: 667.87
• NACRES: NA.21
• PubChem Substance ID: 57651716
• UNSPSC Code: 12352100
• EC Number: 234-293-3
• MDL number: MFCD00167056
• Assay: 99.0-103% (RT)

Propiedades

• Nombre del producto: Potassium antimonyl tartrate trihydrate, purum p.a., 99.0-103% (RT)
• grade: purum p.a.
• Quality Segment: 200
• assay: 99.0-103% (RT)
• loss: ≤2.7% loss on drying
• mp: ≥300 °C (lit.)
• anion traces: chloride (Cl^-): ≤100 mg/kg, sulfate (SO₄^2-): ≤500 mg/kg
• cation traces: Ca: ≤50 mg/kg, Cd: ≤50 mg/kg, Co: ≤50 mg/kg, Cu: ≤50 mg/kg, Fe: ≤50 mg/kg, Na: ≤500 mg/kg, Ni: ≤50 mg/kg, Pb: ≤50 mg/kg, Zn: ≤50 mg/kg
• SMILES string: O.O.O.[K+].[K+].O=C1O[Sb-]23OC1C4O[Sb-]5(OC(C(O2)C(=O)O3)C(=O)O5)OC4=O
• InChI: 1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4
• InChI key: WBTCZEPSIIFINA-UHFFFAOYSA-J

Descripción

General description

Potassium antimonyl tartrate trihydrate is a trivalent antimony compound. It has been reported to be a leishmanicidal compound and exhibits more toxic action than pentavalent antimony (Pentostam) against Leishmania species. Three-dimensional X-ray and white radiation neutron diffraction methods have been reported to investigate the crystal structure of its optically active form (dipotassium di-μ-d-tartrato (4)-bis(antimonate(III)) trihydrate). Unit cell dimensions reported were: a = 11.192(2), b = 11.696(3), and c = 25.932(5)Å.

Application

Potassium antimonyl tartrate trihydrate may be used as an Sb(III)-containing drug to investigate its ability to induce cell death associated with DNA fragmentation in axenic amastigotes of Leishmania infantum.

Información de seguridad

• Pictogramas: GHS06,GHS09
• Palabra de advertencia: Danger
• Códigos de peligro: H301,H315,H317,H332,H411
• Indicaciones de precaución: P261 - P273 - P280 - P301 + P310 - P302 + P352 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Skin Irrit. 2 - Skin Sens. 1
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• EPI (equipos de protección individual): dust mask type N95 (US), Eyeshields, Faceshields, Gloves