37022

(−)-Scopolamine hydrochloride

analytical standard

• Sinónimos: Hyoscine hydrochloride, Scopine tropate
• Fórmula empírica (notación de Hill): C₁₇H₂₁NO₄ · HCl
• Número CAS: 55-16-3
• Peso molecular: 339.81
• UNSPSC Code: 85151701
• NACRES: NA.24
• PubChem Substance ID: 329755587
• EC Number: 200-225-6
• Beilstein/REAXYS Number: 4168778
• MDL number: MFCD00058096
• eCl@ss: 32160703

Propiedades

• grade: analytical standard
• Quality Segment: 100
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): cleaning products; cosmetics; food and beverages; personal care
• format: neat
• storage temp.: −20°C
• SMILES string: Cl.[H][C@]12C[C@H](C[C@]([H])(N1C)[C@]3([H])O[C@]23[H])OC(=O)[C@H](CO)c4ccccc4
• InChI: 1S/C17H21NO4.ClH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13-,14+,15-,16+;/m1./s1
• InChI key: KXPXJGYSEPEXMF-MOUKNHLCSA-N
• Gene Information: human ... CHRM1(1128)

Descripción

General description

(−)-Scopolamine hydrochloride belongs to the class of naturally occurring tropane alkaloids of medicinal interest, found in several members of the Solanaceae family, commonly Atropa belladonna and representatives of the genera Datura and Duboisia.

For the analysis of the phytotoxins.

Application

(−)-Scopolamine hydrochloride may be used as a precursor for the preparation of scopolamine, employed as an analytical standard for the quantification of the scopolamine in the floral nectar and plant organs of Datura species using various chromatographic techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Competitive nonselective muscarinic acetylcholine antagonist.

Competitive nonselective muscarinic acetylcholine antagonist. Scopolamine-induced amnesia in laboratory animals is a commonly-used model of memory deficit.

Preparation Note

Dried down, concentration of (S)-(-)-Scopolamine (free base) after reconstitution ~100μg/mL

Analysis Note

purity : ≥96.0% (HPLC)

Información de seguridad

• Pictogramas: GHS06,GHS05
• Palabra de advertencia: Danger
• Códigos de peligro: H300 + H310 + H330,H317,H318
• Indicaciones de precaución: P260 - P262 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Sens. 1
• Clase de almacenamiento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable