340855

Glutaraldehyde solution

50 wt. % in H₂O

• Sinónimos: Glutaric dialdehyde solution, Pentane-1,5-dial
• Fórmula lineal: OHC(CH₂)₃CHO
• Número CAS: 111-30-8
• Peso molecular: 100.12
• UNSPSC Code: 12352114
• NACRES: NA.21
• PubChem Substance ID: 24860868
• MDL number: MFCD00007025
• Beilstein/REAXYS Number: 605390
• Form: liquid

Propiedades

• vapor density: 1.05 (vs air)
• Quality Segment: 200
• vapor pressure: 15 mmHg ( 20 °C)
• form: liquid
• concentration: 50 wt. % in H₂O
• technique(s): electron microscopy: suitable, immunoblotting: suitable, immunohistochemistry: suitable
• color: colorless
• refractive index: n20/D 1.42
• mp: -21 °C ((-6 °F))
• solubility: water: soluble
• density: 1.106 g/mL at 25 °C
• suitability: suitable for microfluidics/nanofluidics
• application(s): cell analysis; genomic analysis; life science and biopharma; sample preparation
• SMILES string: [H]C(CCCC([H])=O)=O
• InChI: 1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2
• InChI key: SXRSQZLOMIGNAQ-UHFFFAOYSA-N

Descripción

General description

Glutaraldehyde (Glutaric dialdehyde, Pentane-1,5-dial) is an aliphatic dialdehyde that can be employed as an effective biochemical reagent for various purposes such as a protein crosslinker, enzyme immobilization in microscopy, histochemistry, and cytochemistry. It serves as an amine-reactive homobifunctional crosslinker and a cell fixative before SDS-PAGE, staining, or electron microscopy, making it suitable for a wide range of morphological studies.

Glutaraldehyde is capable of efficiently crosslinking amine and hydrazine derivatives to proteins and other amine-containing polymers. Notably, in certain reactions, biotin hydrazides have been directly coupled to nucleic acids using glutaraldehyde, presenting a potential utility in conjugating fluorescent hydrazides and hydroxylamines to DNA. In histology studies, Glutaraldehyde is also employed to preserve tissue sections and prepare them for closer examination.

Application

Glutaraldehyde may be used in the following studies:

• To compose the fixative solution (Glutaraldehyde + Paraformaldehyde + NaPO₄) for use in high-resolution light microscopy and electron microscopy studies.
• To study the conjugation of goat anti-horseradish peroxidase with alkaline phosphatase by a reported method.
• To compose the primary fixative, which is employed to protect the deterioration of cytoplasmic features of yeast cells during permanganate fixation.

Cross-linking agent for gelatin, poly(vinyl alcohol), and polyheptapeptides.

Features and Benefits

• Versatile and adaptable for wide variety of research applications
• Ready-made solution reduces the need for preparation time

Other Notes

For additional information on our range of Biochemicals, please complete this form.

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Información de seguridad

• Pictogramas: GHS06,GHS08,GHS05,GHS09
• Palabra de advertencia: Danger
• Códigos de peligro: H302,H314,H317,H331,H334,H335,H410
• Indicaciones de precaución: P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
• Órganos diana: Respiratory system
• supp_hazards: EUH071
• Clase de almacenamiento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials