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Merck

03117057001

Roche

Bovine Serum Albumin Fraction V, heat shock, fatty acid free

from bovine serum

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About This Item

UNSPSC Code:
12352106
NACRES:
NA.21

biological source

bovine

Quality Level

assay

≥98%

form

lyophilized

packaging

pkg of 100 g

manufacturer/tradename

Roche

pH

~7.0

shipped in

wet ice

storage temp.

2-8°C

General description

BSA is a single polypeptide chain consisting of about 583 amino acid residues and no carbohydrates. At pH 5-7, it contains 17 intra-chain disulfide bridges and one sulfhydryl group.

Application

  • Pharmacological assays; ion-binding, transport, or immunological studies
  • Fatty acid and lipid research
  • Stabilization of proteins and enzymes against proteolysis and denaturation

Biochem/physiol Actions

The fatty acids that are insoluble in circulating plasma are transported primarily by serum. The human serum albumin and bovine serum albumin share 76% sequence homology. Being the most abundant protein in the circulatory system, it participates in the maintenance of blood pH and carries several endogenous and exogenous compounds, including fatty acids, metal, amino acids, steroids and drugs.

Quality

Purity: ≥98% albumin (electrophoresis), ≥98% protein
Contaminants: ≤1.2mg total fatty acids/g dry powder, ≤30ppm heavy metals, immunoglobulins are not detectable (by Ouchterlony)

Specifications

Moisture: ≤5%

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

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Putnam F, et al.
The Plasma Proteins: Structure, Function, and Genetic Control, 5 (2012)
Emilio P Mottillo et al.
Methods in enzymology, 538, 263-278 (2014-02-18)
Intracellular lipolysis is an important cellular process in key metabolic tissues, and while much is known about the enzymatic basis of lipolysis, our understanding of how these processes are organized and regulated within cells is incomplete. Lipolysis takes place on
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Dendritic spines of striatal Medium Spiny Neurons (MSNs) receive converging dopaminergic and glutamatergic inputs. These spines undergo experience-dependent structural plasticity following repeated drug administration and during disease states like Huntington's and Parkinson's. Thus, understanding the molecular mechanisms leading to structural
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Science signaling, 3(137), pl2-pl2 (2010-09-03)
Controlled production of reactive oxygen species leads to reversible oxidation of protein tyrosine phosphatases (PTPs) and has emerged as an important tier of regulation over phosphorylation-dependent signal transduction. We present a modified cysteinyl-labeling assay that detects reversible oxidation of members

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