This particle is considered to be non-porous. The beads act as a separate gel phase rather than as a porous solid.
8.55014
NovaSyn®TG amino resin (130 µm)
Novabiochem®
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About This Item
Código UNSPSC:
13111023
NACRES:
NA.22
En este momento no podemos mostrarle ni los precios ni la disponibilidad
Nivel de calidad
Línea del producto
NovaSyn® TG
Novabiochem®
Formulario
beads
idoneidad de la reacción
reaction type: Fmoc solid-phase peptide synthesis
fabricante / nombre comercial
Novabiochem®
aplicaciones
peptide synthesis
grupo funcional
amine
temp. de almacenamiento
2-30°C
Descripción general
NovaSyn TG amino resin is a composite of low cross-linked polystyrene and 3000-4000 M.W. polyethylene glycol [1,2,3], in which the PEG chains have been terminally functionalized with an amino group. The 130 μm beads have a narrow size distribution, high diffusion rates and excellent swelling across a wide range of solvents from toluene to water, making them ideally suited to the synthesis of serial and parallel libraries by organic solid phase synthesis. This resin can be easily converted into other supports suitable for use in SPOS by acylation with the appropriate carboxylic acid-containing linker. For example, Hutchins and Chapman [4] have coupled Riniker′s HMPB linker to this resin and used it to prepare a range of ureas derived from glutamic acid.
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Literature references
[1] W. Rapp, et al. in ′Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium′, R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 205.
[2] L. Zhang, et al. in ′Peptides 1990, Proc. 21st European Peptide Symposium′, E. Giralt & D. Andreu (Eds), ESCOM, Leiden, 1990, pp.196.
[3] E. Bayer (1991) Angew. Chem. Int. Ed. Engl., 30,113.
[4] S. M. Hutchins & K. T. Chapman (1994) Tetrahedron Lett., 35, 4055.
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Literature references
[1] W. Rapp, et al. in ′Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium′, R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 205.
[2] L. Zhang, et al. in ′Peptides 1990, Proc. 21st European Peptide Symposium′, E. Giralt & D. Andreu (Eds), ESCOM, Leiden, 1990, pp.196.
[3] E. Bayer (1991) Angew. Chem. Int. Ed. Engl., 30,113.
[4] S. M. Hutchins & K. T. Chapman (1994) Tetrahedron Lett., 35, 4055.
Ligadura / enlace
Replaces: 01-64-0094
Nota de análisis
Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.30 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result
This resin is a composite of low-crossed linked polystyrene and 3000-4000 M.W. polyethylene glycol, which has been terminally amino functionalised. 130µm beads.
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.30 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result
This resin is a composite of low-crossed linked polystyrene and 3000-4000 M.W. polyethylene glycol, which has been terminally amino functionalised. 130µm beads.
Información legal
NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 1
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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