475828

β₂-Microglobulin, Human, Recombinant, E. coli

• Sinónimos: rhβ₂M
• NACRES: NA.25
• UNSPSC Code: 12352202
• Form: lyophilized

Propiedades

• form: lyophilized
• Quality Segment: 100
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, avoid repeated freeze/thaw cycles
• solubility: aqueous buffer: soluble
• shipped in: wet ice
• storage temp.: −20°C

Descripción

General description

Recombinant, human β₂-microglobulin fused at the N-terminus to a His•Tag sequence and expressed in E. coli. Subsequently cleaved with CNBr to remove the His•Tag sequence. Extracellular protein that is non-covalently associated with the α-chains of class I MHC molecules. Used as a marker for various tumors and for kidney disease. The purified protein functions similarly to the native protein in in vitro models of amyloid fibril extension.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Analysis Note

single band by SDS-PAGE

Other Notes

Sugg, S.V., et al. 1981. Proc. Natl. Acad. Sci. USA 78, 6613.
Berggard, I., and Bearn, G. 1968. J. Biol. Chem. 243, 4095.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 1
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable