474500

4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide

Single spot by TLC, solid, N-acetyl-α-D-glucosaminidase substrate, Calbiochem^®

• Sinónimos: 4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide, 4-Methylumbelliferyl-2-acetamido-2-deoxy-α-D-glucopyranoside
• Fórmula empírica (notación de Hill): C₁₈H₂₁NO₈
• Número CAS: 80265-04-9
• Peso molecular: 379.36
• MDL number: MFCD00036771
• UNSPSC Code: 51111800
• NACRES: NA.21
• Form: solid
• Storage condition: OK to freeze, desiccated, protect from light

Propiedades

• Nombre del producto: 4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide, Ultrasensitive, fluorogenic substrate for assay of N-acetyl-α-D-glucosaminidase. Can be used to test for Sanfilippo syndrome B.
• Quality Segment: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, desiccated, protect from light
• impurities: <0.05% 4-methylumbelliferone, <0.2% β-anomer
• color: white
• solubility: DMF: soluble, DMSO: soluble
• shipped in: ambient
• storage temp.: 10-30°C
• SMILES string: N([C@H]1[C@H](O[C@@H]([C@H]([C@@H]1O)O)CO)Oc2cc3[o][c](cc(c3cc2)C)=O)C(=O)C
• InChI: 1S/C18H21NO8/c1-8-5-14(22)26-12-6-10(3-4-11(8)12)25-18-15(19-9(2)21)17(24)16(23)13(7-20)27-18/h3-6,13,15-18,20,23-24H,7H2,1-2H3,(H,19,21)/t13-,15-,16-,17-,18+/m1/s1
• InChI key: QCTHLCFVVACBSA-FGTAOJJYSA-N

Descripción

General description

Ultrasensitive, fluorogenic substrate for assay of N-acetyl-α-D-glucosaminidase. Can be used to test for Sanfilippo B syndrome. Excitation maximum: 360 nm; emission maximum: 440 nm.

Preparation Note

Unstable in solution; reconstitute just prior to use.

Analysis Note

single spot by TLC

Other Notes

Marsh, J., and Fensom, A.H. 1985. Clin. Genet.27, 258.
Chow, P., and Weissmann, B. 1981. Carbohydr. Res. 96, 87.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable