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389561

Sigma-Aldrich

Hyaluronidase, Streptomyces hyaluronlyticus nov. sp.

Sinónimos:

Hyaluronidase, Streptomyces hyaluronlyticus nov. sp.

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About This Item

Número de CAS:
37326-33-3
Comisión internacional de enzimas:
3.2.1.35 (BRENDA, IUBMB)
MDL number:
MFCD00131351
UNSPSC Code:
12352202
NACRES:
NA.54

conjugate

conjugate (Glucosaminoglycan)

Quality Level

100

form

lyophilized powder

specific activity

≥2000 units (A280)

packaging

ampule of ≥100 U (1 U = 1 TRU (Turbidity Reducing Unit))

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

0.5 M acetate, pH 6.0: 30 U/mL
water: 30 U/mL

foreign activity

protease ≤0.05 U/ampule (pH 6.0)

shipped in

ambient

storage temp.

2-8°C

Categorías relacionadas

General description

Native hyaluronidase from Streptomyces hyaluronlyticus nov. species. Catalyzes the degradation of hyaluronic acid. Produces δ4,5-unsaturated tetra- and hexasaccharides.
Native hyaluronidase from Streptomyces hyaluronlyticus nov. species. Catalyzes the degradation of hyaluronic acid. Produces δ4,5-unsaturated tetra- and hexasaccharides.



Please Note: The appearance of this product can vary from gray cottony fibers to balled up droplets with no change in quality.

Warning

Toxicity: Standard Handling (A)

Unit Definition

One TRU (Turbidity Reducing Unit = 1 U) is defined as the amount of enzyme that will hydrolyze 50% of hyaluronic acid, determined by a 50% reduction in turbidity, in 30 min at 60°C pH 6.0.

Reconstitution

Following reconstitution, store in the refrigerator (4°C). Stock solutions prepared in water are stable for up to 2 weeks at 4°C and stock solutions prepared in 500 mM acetate buffer, pH 6.0, are stable for up to 1 month at 4°C.

Other Notes

Baker, J.R., et al. 2002. Biochem. J.365, 317.
Mogelerskii, M.S. 1964. Fed. Proc. 23, T559.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H334

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Jennifer E Rowley et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 68(1), 75-91 (2019-11-13)
Hyaluronan (HA) is a ubiquitous component of the extracellular matrix. The spatial-temporal localization of HA can be visualized in situ using biotinylated HA binding proteins (HABPs). This assay is sensitive to fixation conditions, and there are currently no best practices

Artículos

Glycosaminoglycans and Proteoglycans

Uncover more about glycosaminoglycans and proteoglycans including the structure of glycosaminoglycans (GAGs), the different types of GAGs, and their functions.

Glycosaminoglycans and Proteoglycans

Uncover more about glycosaminoglycans and proteoglycans including the structure of glycosaminoglycans (GAGs), the different types of GAGs, and their functions.

Glycosaminoglycans and Proteoglycans

Uncover more about glycosaminoglycans and proteoglycans including the structure of glycosaminoglycans (GAGs), the different types of GAGs, and their functions.

Glycosaminoglycans and Proteoglycans

Uncover more about glycosaminoglycans and proteoglycans including the structure of glycosaminoglycans (GAGs), the different types of GAGs, and their functions.

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