25972-M

2-Deoxy-D-glucose

Non-metabolizable derivative of glucose that can be carried by the glucose carrier in human erythrocytes. An indirect inhibitor of hexokinase. Reported to reduce the incidence of doxorubicin-induced apoptosis.

• Sinónimos: 2-Deoxy-D-glucose
• Fórmula empírica (notación de Hill): C₆H₁₂O₅
• Número CAS: 154-17-6
• Peso molecular: 164.16
• UNSPSC Code: 12352201
• NACRES: NA.79
• MDL number: MFCD00151328

Propiedades

• Quality Segment: 100
• description: RTECS - MQ3325000; Merck USA index - 14, 2904
• assay: ≥98% (HPLC)
• form: powder
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: off-white to white
• solubility: water: 5 mg/mL
• storage temp.: 2-8°C
• SMILES string: O1C(CC(C(C1CO)O)O)O
• InChI: 1S/C6H12O5/c7-2-4-6(10)3(8)1-5(9)11-4/h3-10H,1-2H2
• InChI key: PMMURAAUARKVCB-UHFFFAOYSA-N

Descripción

General description

Non-metabolizable derivative of glucose that can be carried by the glucose carrier in human erythrocytes. An indirect inhibitor of hexokinase. Reported to reduce the incidence of doxorubicin-induced apoptosis.

Preparation Note

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.

Other Notes

Thakkar, N.S., and Potten, C.S. 1993. Cancer Res. 53, 2057.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable