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Merck
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Documentos clave

07-1406

Sigma-Aldrich

Anti-GLUT-5 Antibody, a.a. 490-502

serum, from rabbit

Sinónimos:

Fructose transporter, Glucose transporter type 5, small intestine, glucose transporter-like protein 5, solute carrier family 2 (facilitated glucose transporter),

member 5, solute carrier family 2 (facilitated glucose/fructose

transporte

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

100

forma del anticuerpo

serum

tipo de anticuerpo

primary antibodies

clon

polyclonal

reactividad de especies

rat, guinea pig, mouse

técnicas

western blot: suitable

Nº de acceso UniProt

P22732

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

mouse ... Slc2A5(56485)

Descripción general

A cytochalasin B-sensitive carrier located in the membrane, GLUT-5 appears to be primarily functional as a fructose transporter. It is expressed in the small intestine, and is also found in the skeletal muscle, kidney and adipose tissue but at significantly reduced levels.

Especificidad

Recognizes GLUT-5.

Inmunógeno

Epitope: C-terminus
Synthetic peptide corresponding to the C-terminus of rat GLUT-5 (aa 490-502) coupled to KLH. The immunogen sequence used is only 53% conserved in mouse.

Aplicación

Anti-GLUT-5 Antibody, a.a. 490-502 detects level of GLUT-5 & has been published & validated for use in WB.
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling

Calidad

Evaluated by Western Blot in Mouse kidney lysate.
Western Blot Analysis: A 1:1000 dilution of this antibody detected GLUT-5 in 10 µg of mouse kidney lysates.

Descripción de destino

Approx. 54 kDa

Ligadura / enlace

Replaces: AB1348

Forma física

Liquid containing 0.05% sodium azide.
Unpurified rabbit serum

Almacenamiento y estabilidad

Store at -20°C in undiluted aliquots for up to 1 year from date of receipt. Avoid repeated freeze-thaw cycles.

Nota de análisis

Control
Mouse kidney lysate.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Irene Zwarts et al.
Scientific reports, 9(1), 9299-9299 (2019-06-28)
Fructose has become a major constituent of our modern diet and is implicated as an underlying cause in the development of metabolic diseases. The fructose transporter GLUT5 (SLC2A5) is required for intestinal fructose absorption. GLUT5 expression is induced in the
High Fructose Corn Syrup Accelerates Kidney Disease and Mortality in Obese Mice with Metabolic Syndrome.
Andres-Hernando, et al.
Biomolecules, 13 (2023)
Ana Andres-Hernando et al.
Cell metabolism, 32(1), 117-127 (2020-06-06)
Intake of fructose-containing sugars is strongly associated with metabolic syndrome. Compared with other sugars, dietary fructose is uniquely metabolized by fructokinase. However, the tissue-specific role of fructokinase in sugar-induced metabolic syndrome, and the specific roles of glucose and fructose in

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