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Merck

N-017

Supelco

Normeperidine solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C14H19NO2
Número de CAS:
Peso molecular:
233.31
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

O=C(OCC)C1(C2=CC=CC=C2)CCNCC1

InChI

1S/C14H19NO2/c1-2-17-13(16)14(8-10-15-11-9-14)12-6-4-3-5-7-12/h3-7,15H,2,8-11H2,1H3

InChI key

QKHMFBKXTNQCTM-UHFFFAOYSA-N

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General description

Normeperidine is a toxic primary metabolite of the opioid analgesic meperidine. This Certified Snap-N-Spike® Solution is suitable for use in pain prescription monitoring, clinical toxicology, urine drug testing, or forensic analysis by LC-MS/MS, LC/MS or GC/MS. Meperidine, a synthetic opioid with effects similar to morphine, is used as a painkiller.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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J L Plummer et al.
Toxicology, 95(1-3), 37-44 (1995-01-06)
This study investigated behavioural effects of the toxic pethidine metabolite, norpethidine, in rats and its interactions with reserpine, apomorphine and physostigmine. Following intraperitoneal administration, brain concentrations of norpethidine reached a plateau after 20-40 min and remained elevated for 2 h.
Meperidine in patient-controlled analgesia: a near-fatal mishap.
R J Geller
Anesthesia and analgesia, 76(3), 655-657 (1993-03-01)
Thomas T Simopoulos et al.
Archives of surgery (Chicago, Ill. : 1960), 137(1), 84-88 (2002-01-31)
Intravenous patient-controlled analgesia (IV PCA) meperidine hydrochloride can be used with a reasonable margin of safety. A retrospective review was performed of 355 medical records of patients receiving IV PCA meperidine treatment. Four groups of patients were defined, based on
J H Vranken et al.
Acta anaesthesiologica Scandinavica, 49(5), 665-670 (2005-04-20)
Intrathecal administration of meperidine, an opioid with local anesthetic activity, can induce analgesia in patients with intractable cancer pain. However, continuous intrathecal administration may result in the accumulation of normeperidine, responsible for central nervous system toxicity. Ten patients with neuropathic
W D Ngan Kee et al.
Anaesthesia and intensive care, 24(1), 51-55 (1996-02-01)
We evaluated a disposable device (Baxter PCA Infusor) for patient-controlled epidural analgesia (PCEA) using pethidine in twenty women after lower segment caesarean section. Efficacy, as measured by visual analogue pain scores, was comparable with historical controls from PCEA studies using

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