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H3275

Sigma-Aldrich

3-Hydroxy-5-methylisoxazole

≥90%

Sinónimos:

Hymexazol

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About This Item

Fórmula empírica (notación de Hill):
C4H5NO2
Número de CAS:
10004-44-1
Peso molecular:
99.09
EC Number:
233-000-6
MDL number:
MFCD00144468
UNSPSC Code:
12352100
PubChem Substance ID:
57654246
NACRES:
NA.22

assay

≥90%

storage temp.

2-8°C

SMILES string

CC1=CC(=O)NO1

InChI

1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)

InChI key

KGVPNLBXJKTABS-UHFFFAOYSA-N

Application

3-Hydroxy-5-methylisoxazole can be used as a reactant to synthesize:
  • 3-Oxoisoxazole-2(3H)-carboxamides by reacting with dimethyl-carbamoyl chloride in the presence of potassium t-butoxide.
  • Hydroxymethyl-2-propen-1-yl-5-methyl-3(2H)-isoxazolone via ring-opening reaction with vinyl oxirane.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Journal of agricultural and food chemistry, 68(8), 2418-2425 (2020-02-06)
Two biosynthetically related new metabolites, eucalyptacid A (1) and eucalactam B (2), along with six known compounds (3-8), eugenitol (3), cytosporone C (4), 4-hydroxyphenethyl alcohol (5), 1-(4-hydroxyphenyl)ethane-1,2-diol (6), N-(2-hydroxy-2-phenylethyl)acetamide (7), and phomopene (8), were isolated from the solid rice cultures
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Bioassay-guided fractionation of the fermentation extract of Xylaria sp. XC-16, an endophyte from Toona sinensis led to the isolation of two new cytochalasans cytochalasin Z27, 1, and cytochalasin Z28, 2, along with three known compounds seco-cytochalasin E, 3, and cytochalasin
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Hymexazol is an efficacious and widely used fungicide. However, its environmental toxicological assessment has not been well documented. It had no report of its toxicity to fish embryo. Fish embryo acute toxicity tests are highly predictive of aquatic embryotoxicity outcome.
[An experimental study of carcinogenic activity of bucide and its effects on the reproductive function].
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Research on solarization efficacy has examined the critical temperature and minimum exposure time to inactivate soilborne pathogens. Most mathematical models focus on survival of inoculum subjected to a constant heat regime rather than an intermittent heat regime that better simulates
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