D33454
1,3-Diphenyl-1,3-propanedione
98%
Sinónimos:
Dibenzoylmethane
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About This Item
Fórmula lineal:
(C6H5CO)2CH2
Número de CAS:
Peso molecular:
224.25
Beilstein:
514910
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de la sustancia en PubChem:
NACRES:
NA.22
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Ensayo
98%
Formulario
crystals
bp
219-221 °C/18 mmHg (lit.)
mp
77-79 °C (lit.)
cadena SMILES
O=C(CC(=O)c1ccccc1)c2ccccc2
InChI
1S/C15H12O2/c16-14(12-7-3-1-4-8-12)11-15(17)13-9-5-2-6-10-13/h1-10H,11H2
Clave InChI
NZZIMKJIVMHWJC-UHFFFAOYSA-N
Información sobre el gen
human ... ACHE(43) , BCHE(590) , CES1(1066)
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Descripción general
1,3-Diphenyl-1,3-propanedione also known as Dibenzoylmethane, a symmetrical ß-diketone with the ability to form strong intra and intermolecular hydrogen bonds is commonly used to produces a Schiff base in reaction with benzidine.
Aplicación
- A radical-anion chain mechanism following dissociative electron transfer reduction of the model prostaglandin endoperoxide, 1,4-diphenyl-2,3-dioxabicyclo[2.2.1]heptane.: This study explores the unique chemical properties of 1,3-Diphenyl-1,3-propanedione in the context of electron transfer reactions. The research unveils its potential in creating advanced prostaglandin models, crucial for pharmaceutical applications and drug synthesis. This application is especially significant in the context of prostaglandin biosynthesis, offering a pathway to new drug development strategies within the pharmaceutical industry and biochemical research (Magri & Workentin, 2008).
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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Chia-Jui Weng et al.
Journal of agricultural and food chemistry, 57(12), 5235-5243 (2009-05-16)
While lung cancer accounts for approximately 20% of cancer diagnoses, it is the leading cause of tumor-related deaths. The apoptotic effects of 3,5,4'-trihydroxystilbene (resveratrol), dibenzoylmethane (DBM), and their analogues on human lung cancer cells are generally unclear. The aims of
Preetha Anand et al.
Biochemical pharmacology, 82(12), 1901-1909 (2011-09-20)
Curcumin, a diferuloylmethane, has been shown to exhibit anti-inflammatory and anti-proliferative activities. Whereas curcumin has both a Michael acceptor and a Michael donor units, its analogues dibenzoylmethane (DBM, a component of licorice) and dibenzoylpropane (DBP) have a Michael donor but
Tin Oo Khor et al.
Cancer research, 69(17), 7096-7102 (2009-08-27)
Dibenzoylmethane (DBM), a minor beta-diketone constituent of licorice, has been shown to exhibit antineoplastic effects in prostate cancer cell lines by induction of cell cycle arrest and regulation of androgen receptor expression. In the present study, we investigated the in
Abdou Saad El-Tabl et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 71(1), 90-99 (2008-02-05)
A new series of mono and binuclear Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II), La(III), Ru(III), Hf(IV), ZrO(II) and UO2(II) complexes of phenylaminodibenzoylhydrazone have been synthesized and characterized by elementals analyses, IR UV-vis spectra, magnetic moments, conductances, thermal analyses (DTA and
Yuichi Masuda et al.
The journal of physical chemistry. A, 116(18), 4485-4494 (2012-04-19)
Despite the importance of ultrafast (time scale exceeding 10(-11) s) intramolecular proton transfer (PT) events between electronic ground states in solution, experimental determination of the rates of such reactions has not yet been accomplished because of the limitations of the
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