900555
(N-Isocyanoimino)triphenylphosphorane
95%
Sinónimos:
Pinc
About This Item
Productos recomendados
Quality Level
assay
95%
form
solid
application(s)
peptide synthesis
InChI
1S/C19H15N2P/c1-20-21-22(17-11-5-2-6-12-17,18-13-7-3-8-14-18)19-15-9-4-10-16-19/h2-16H
InChI key
NIDTXBFHPXMXTR-UHFFFAOYSA-N
General description
Application
Features and Benefits
- Bench-stable solid: Pinc is a stable reagent that can be easily handled and stored.
- Facilitates cyclization and incorporation of conformational control element: Pinc enables the formation of peptide macrocycles with a desired conformation, leading to improved drug properties.
- Amphoteric properties: Pinc′s amphoteric nature allows for the design of new multicomponent reactions, expanding its synthetic capabilities.
- Desired drug properties: The resulting peptide macrocycles exhibit enhanced membrane permeability, lipophilicity, and aqueous solubility, making them desirable for drug development.
- Versatile transformations: Pinc′s ability to form oxadiazoles opens up opportunities for the development of novel synthetic transformations.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Artículos
Isocyanides are widely used reagents in organic synthesis, with applications ranging from materials science to drug discovery.
Contenido relacionado
The Yudin laboratory is known for the development of amphoteric molecules and their application in synthesis. The corresponding reagents possess nucleophilic and electrophilic functional groups that do not prematurely react with each other.
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