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679437

Sigma-Aldrich

4-(Bromomethyl)phenylboronic acid

Sinónimos:

α-Bromo-p-tolueneboronic acid, p-Boronobenzyl bromide

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About This Item

Fórmula lineal:
BrCH2(C6H4)B(OH)2
Número de CAS:
68162-47-0
Peso molecular:
214.85
MDL number:
MFCD01318113
UNSPSC Code:
12352103
PubChem Substance ID:
24885493
NACRES:
NA.22

form

solid

Quality Level

100

mp

173-177 °C

storage temp.

2-8°C

SMILES string

OB(O)c1ccc(CBr)cc1

InChI

1S/C7H8BBrO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4,10-11H,5H2

InChI key

PDNOURKEZJZJNZ-UHFFFAOYSA-N

General description

May contain varying amounts of anhydride

Application

Reactant involved in:
  • Design of boronic acid-based autotaxin inhibitors
  • Synthesis of boronated phosphonium salts
  • Studies of incorporation of boronic acid groups to enhance gene transfection capability
  • Investigations of the effect of boronic acid-positioning in optical glucose-sensing ensemble

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Ding Ma et al.
ACS applied materials & interfaces, 12(8), 9032-9040 (2020-01-28)
MicroRNAs (miRNAs) therapy has shown to have great promise for the treatment of androgen-independent prostate cancer (AIPC) due to the low efficiency of hormonal therapy. However, instability of RNA and inefficiency of RNA therapy limit the use of miRNAs in
Yu-Lin Su et al.
Journal of controlled release : official journal of the Controlled Release Society, 321, 159-173 (2020-02-12)
Compact nanohybrids can potentially unite various therapeutic features and reduce side effects for precise cancer therapy. However, the poor accumulation and limited tumor penetration of drugs at the tumor impede the manifestation of nanomedicine. We developed a rabies virus glycoprotein
Chongyi Liu et al.
Advanced healthcare materials, 5(5), 584-592 (2016-01-21)
Cationic dendrimers are widely used as nonviral gene vectors, however, current gene materials based on dendrimers are either little effective or too toxic on the transfected cells. Here, a facile strategy is presented to prepare high efficient dendrimers with low

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