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Merck

675075

Sigma-Aldrich

8-Mercaptooctanoic acid

95%

Sinónimos:

8-Thiooctanoic acid, MOA

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About This Item

Fórmula empírica (notación de Hill):
C8H16O2S
Número de CAS:
Peso molecular:
176.28
Número MDL:
Código UNSPSC:
12352103
ID de la sustancia en PubChem:
NACRES:
NA.23

Nivel de calidad

Ensayo

95%

índice de refracción

n20/D 1.4808

densidad

1.0326 g/mL at 25 °C

temp. de almacenamiento

−20°C

cadena SMILES

OC(=O)CCCCCCCS

InChI

1S/C8H16O2S/c9-8(10)6-4-2-1-3-5-7-11/h11H,1-7H2,(H,9,10)

Clave InChI

FYEMIKRWWMYBFG-UHFFFAOYSA-N

Descripción general

8-Mercaptooctanoic acid (MOA) is an carboxylic acid terminated alkanethiol that forms self-assembled monolayers (SAMs) that facilitate subsequent surface immobilization of other molecular species.
8-mercaptooctanoic acid (MOA) forms a self-assembled monolayer (SAM) on the surface of nanoparticles. MOA consists of thiol and carboxylic groups which helps in the surface treatment of different nanoparticles.

Aplicación

MOA is a used as a SAM for surface modification of gold electrodes for quartz crystal microbalance (QCMB) measurement. It may be used as a monolayer that facilitates ferritin absorption on gold electrodes for uptake of excess iron in the cell. It may also be used for preparation of nitric oxide based gold nanoparticles (NO-AuNPs) for macrophage photo-thermal therapy under NIR irradiation.
MOA may form SAM that can be used in the surface modification of gold electrodes which are useful for the study of surface characteristics of ferritin. It may also be used to form SAM with hydrophilic end groups to be used as a protective coating on the electrodes for efficient electron transport in semiconductor devices.
This compound is used to produce hydrophilic SAMs. The resulting monolayers which are terminated with carboxylic acids can be further functionalized to introduce more complex end groups. Can also be used to form a protective barrier monolayer to allow deposition of a passivating oxide layer.

Otras notas

This product should be stored in the freezer, 0 to -20 °C

Pictogramas

Exclamation mark

Palabra de señalización

Warning

Frases de peligro

Clasificaciones de peligro

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Visite la Librería de documentos

Chapman, R. G.; et al.
Journal of the American Chemical Society, 122, 8308-8308 (2000)
George Haddad et al.
PloS one, 8(10), e78244-e78244 (2013-10-22)
The microvascular endothelium of the kidney glomerulus is injured in Shiga-like toxigenic bacterial infection, genetic or acquired loss of complement regulatory protein function, and allo-immune responses of solid-organ or bone marrow transplantation. Existing models of diseases with glomerular endothelial cell
Preiner, M. J.; Melosh, N. A.
Applied Physics Letters, 92, 213301-213301 (2008)
Surface-electrochemistry of ferritin adsorbed on 8-mercaptooctanoic acid-modified gold electrodes.
Ritzert NL, et al.
Electrochemical Communications, 11(4), 827-830 (2009)
Hongbo Guo et al.
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