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602841

Sigma-Aldrich

Oxygen-17O2

90 atom % 17O

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About This Item

Fórmula lineal:
17O2
Número de CAS:
67321-81-7
Peso molecular:
34.00
MDL number:
MFCD00084250
UNSPSC Code:
12142200
PubChem Substance ID:
329758853

isotopic purity

90 atom % 17O

assay

99% (CP)

form

gas

mass shift

M+2

SMILES string

[17O]=[17O]

InChI

1S/O2/c1-2/i1+1,2+1

InChI key

MYMOFIZGZYHOMD-ZDOIIHCHSA-N

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General description

Oxygen-17O2 is the isotopic analogue of oxygen.

Application

Oxygen-17O2 can be used
to estimate the cerebral metabolic rate of oxygen consumption (CMRO2) of swine by detection of metabolically produced H217O by rapid T1-weighted proton magnetic resonance imaging.
to understand the altered cerebral oxygen metabolism in glioma via dynamic 17O MRI.
to measure the quantitative and simultaneous measurement of oxygen consumption rates in rat brain and skeletal muscle using 17O MRS imaging.

Packaging

All gas volumes are quoted at Standard Temperature and Pressure (STP) and not at Normal Temperature and Pressure (NTP). One STP Liter is 7.7% more gas than one NTP Liter.
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

pictograms

Flame over circleGas cylinder
GHS03,GHS04

signalword

Danger

hcodes

H270,H280

Hazard Classifications

Ox. Gas 1 - Press. Gas Compr. Gas

Storage Class

2A - Gases

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Sigma-Aldrich

332089

Agua-18O

Hydrogen peroxide-18O2 solution 2-3% in H2O, 90 atom % 18O

Sigma-Aldrich

609978

Hydrogen peroxide-18O2 solution

Eric A Mellon et al.
Journal of neuroscience methods, 179(1), 29-39 (2009-05-12)
Despite the importance of metabolic disturbances in many diseases, there are currently no clinically used methods for the detection of oxidative metabolism in vivo. To address this deficiency, (17)O MRI techniques are scaled from small animals to swine as a
Hannes M Wiesner et al.
Magnetic resonance in medicine, 85(4), 2232-2246 (2020-10-27)
Oxygen-17 (17 O) MRS imaging, successfully used in the brain, is extended by imaging the oxygen metabolic rate in the resting skeletal muscle and used to determine the total whole-body oxygen metabolic rate in the rat. During and after inhalations
Daniel Paech et al.
Radiology, 295(1), 181-189 (2020-02-19)
Background Altered metabolism is a characteristic of cancer. Because of a shift in glucose metabolism from oxidative phosphorylation to lactate production for energy generation, malignant tumors are characterized by increased glycolysis followed by lactic acid fermentation, even in the presence

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