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343862

Sigma-Aldrich

1-Bromoheptadecafluorooctane

99%

Sinónimos:

Heptadecafluorooctyl bromide, Perfluorooctyl bromide

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About This Item

Fórmula lineal:
CF3(CF2)7Br
Número de CAS:
423-55-2
Peso molecular:
498.96
Beilstein/REAXYS Number:
2016022
EC Number:
207-028-4
MDL number:
MFCD00042082
UNSPSC Code:
12352100
PubChem Substance ID:
24861212
NACRES:
NA.22

Quality Level

100

assay

99%

form

liquid

refractive index

n20/D 1.305 (lit.)

bp

142 °C (lit.)

density

1.93 g/mL at 25 °C (lit.)

SMILES string

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Br

InChI

1S/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26

InChI key

WTWWXOGTJWMJHI-UHFFFAOYSA-N

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General description

1-Bromoheptadecafluorooctane (perfluorooctyl bromide) is a perfluorocarbon. Poly(ethylene glycol)ylated polyester nanocapsules of perfluorooctyl bromide were surface-decorated with a RGD (arginine-glycine-aspartic acid) peptide, were used for tumor imaging. Nanocapsules of perfluorooctyl bromide have been developed as dual contrast agent for ultrasonography and Magnetic Resonance Imaging (MRI).

Application

1-Bromoheptadecafluorooctane (perfluorooctyl bromide) can be used as contrast agent in the vascular system for fluorine-19 magnetic resonance imaging or as synthetic oxygen carrier. It was also employed as oxygen carrier in the emulsions used as blood substitutes.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Certificados de análisis (COA)

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Sabah Servaes et al.
Pediatric radiology, 39(4), 393-395 (2009-02-04)
Partial liquid ventilation therapy utilizing perfluorocarbons has been used for patients with severe respiratory distress. Perfluorocarbons such as perflubron have been demonstrated to clear from the lungs shortly after therapy. We present a 13-year-old boy with residual perflubron in his
Sun-Joo Lee et al.
The journal of physical chemistry. B, 114(31), 10086-10096 (2010-08-06)
Perfluorocarbon-based nanoemulsion particles have arisen as promising platforms for the cellular delivery of imaging and therapeutic agents to specific targets. However, current knowledge of the agent delivery mechanism is limited to qualitative and phenomenological models. Lack of detail at the
Allison E McDonald et al.
Biochimica et biophysica acta, 1807(8), 954-967 (2010-11-09)
Oxygenic photosynthesis depends on a highly conserved electron transport system, which must be particularly dynamic in its response to environmental and physiological changes, in order to avoid an excess of excitation energy and subsequent oxidative damage. Apart from cyclic electron
Céline Giraudeau et al.
Angiogenesis, 16(1), 171-179 (2012-10-12)
Molecular imaging with magnetic resonance imaging (MRI) targeted contrast agents has emerged as a promising diagnostic approach in cancer research to detect associated biomarkers. In this work, the potential of (19)F MRI was investigated to detect angiogenesis with α(ν)β(3)-targeted perfluorooctylbromide
Journal of Fluorine Chemistry, 114, 119-126 (2002)
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