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247480

Domiphen bromide

Name: Domiphen bromide
Brand: ALDRICH

97%

Sinónimos:

(Dodecyldimethyl-2-phenoxyethyl)ammonium bromide

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About This Item

Fórmula lineal:

CH₃(CH₂)₁₁N(CH₃)₂(CH₂CH₂OC₆H₅)Br

Número de CAS:

538-71-6

Peso molecular:

414.46

Número CE:

208-702-0

Número MDL:

MFCD00011769

Código UNSPSC:

12352112

ID de la sustancia en PubChem:

24854870

NACRES:

NA.22

Ensayo

97%

Formulario

powder

mp

117-119 °C (lit.)

cadena SMILES

[Br-].CCCCCCCCCCCC[N+](C)(C)CCOc1ccccc1

InChI

1S/C22H40NO.BrH/c1-4-5-6-7-8-9-10-11-12-16-19-23(2,3)20-21-24-22-17-14-13-15-18-22;/h13-15,17-18H,4-12,16,19-21H2,1-3H3;1H/q+1;/p-1

Clave InChI

OJIYIVCMRYCWSE-UHFFFAOYSA-M

Descripción general

Domiphen bromide (DMP) is a quaternary ammonium compound that belongs to the class of phenol ethers. It can be used as a cationic surfactant.

Aplicación

Domiphen Bromide in Antimicrobial Applications: A clinical trial assessed the effectiveness of a mouthwash containing Domiphen Bromide among other quaternary ammonium compounds, showcasing its ability to significantly reduce gingivitis, supporting its use in dental health products (Rosa and Sturzenberger, 1976).
Toxicity and Safety Profile of Domiphen Bromide: A recent study explored the proarrhythmic effects induced by Domiphen Bromide in both in vitro and in vivo models, providing vital safety information crucial for its use in pharmaceutical applications (Long et al., 2021).

Pictogramas

GHS07

Palabra de señalización

Warning

Frases de peligro

H302,H315,H319,H335

Consejos de prudencia

P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Clasificaciones de peligro

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

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Activity and tolerability of domifen bromide in patients affected by acute infectious dental diseases: a double-blind placebo-controlled trial.

F Scaglione et al.

International journal of clinical pharmacology research, 3(5), 357-361 (1983-01-01)

Thirty-one patients (21 M and 10 F), affected by acute infectious dental disease, were treated with domifen bromide (A) or placebo (Pl). It was found that A had a beneficial effect on the results of clinical controls and reduced the

Separation of fulvic acid from soil extracts based on ion-pair formation with a cationic surfactant

Fukushima M, et al.

Analytical Sciences, 22(2), 229-233 (2006)

Thermophysical Studies on Molecular Interactions of Semicarbazide Hydrochloride/Domiphen Bromide in Aqueous Deep Eutectic Solvent Media at Various Temperatures

Majid Q, et al.

Journal of Chemical and Engineering Data, 67(10), 2974-2985 (2022)

Identification and validation of a novel lead compound targeting 4-diphosphocytidyl-2-C-methylerythritol synthetase (IspD) of mycobacteria.

Peng Gao et al.

European journal of pharmacology, 694(1-3), 45-52 (2012-09-15)

Tuberculosis is a serious threat to world-wide public health usually caused in humans by Mycobacterium tuberculosis (M. tuberculosis). It exclusively utilizes the methylerythritol phosphate (MEP) pathway for biosynthesis of isopentenyl diphosphate (IPP) and its isomer dimethylallyl diphosphate (DMAPP), the precursors

Synthesis of PEGylated gold nanostars and bipyramids for intracellular uptake.

Julien R G Navarro et al.

Nanotechnology, 23(46), 465602-465602 (2012-10-26)

A great number of works have focused their research on the synthesis, design and optical properties of gold nanoparticles for potential biological applications (bioimaging, biosensing). For this kind of application, sharp gold nanostructures appear to exhibit the more interesting features

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