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Documentos

219878

Sigma-Aldrich

4-Hydroxyindole

99%

Sinónimos:

4-Indolol, 4-Hydroxyindole

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About This Item

Fórmula empírica (notación de Hill):
C8H7NO
Número de CAS:
2380-94-1
Peso molecular:
133.15
Beilstein/REAXYS Number:
114905
EC Number:
219-177-2
MDL number:
MFCD00005667
UNSPSC Code:
12352100
PubChem Substance ID:
24853151
NACRES:
NA.22

assay

99%

form

solid

mp

97-99 °C (lit.)

SMILES string

Oc1cccc2[nH]ccc12

InChI

1S/C8H7NO/c10-8-3-1-2-7-6(8)4-5-9-7/h1-5,9-10H

InChI key

NLMQHXUGJIAKTH-UHFFFAOYSA-N

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General description

Glucouridination of 4-hydroxyindole by human uridine 5′-diphospho-glucuronosyltransferase has been repotrted.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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4-Bromoindole 96%

Sigma-Aldrich

524336

4-Bromoindole

Psilocybin solution 1.0 mg/mL in acetonitrile: water (1:1), ampule of 1 mL, certified reference material, Cerilliant®

Supelco

P-097

Psilocybin solution

7-Methylindole 97%

Sigma-Aldrich

M51490

7-Methylindole

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Archiv der Pharmazie, 349(3), 211-223 (2016-02-09)
β-Adrenergic receptor antagonists are important therapeutics for the treatment of cardiovascular disorders. In the group of β-blockers, much attention is being paid to the third-generation drugs that possess important ancillary properties besides inhibiting β-adrenoceptors. Vasodilating activity of these drugs is
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Journal of pharmaceutical and biomedical analysis, 140, 215-222 (2017-04-04)
Each year, synthetic cannabinoids are occurring in high numbers in the illicit drug market, but data on their pharmacology and toxicology are scarcely available. Therefore, a pilot study was performed to assess adverse effects of JWH-018, which is one of
Shalenie P den Braver-Sewradj et al.
Current drug metabolism, 19(4), 370-381 (2018-01-11)
Inter-individual variability in hepatic drug metabolizing enzyme (DME) activity is a major contributor to heterogeneity in drug clearance and safety. Accurate data on expression levels and activities of DMEs is an important prerequisite for in vitro-in vivo extrapolation and in
Alexandra M Adams et al.
Metabolic engineering, 56, 111-119 (2019-09-25)
Psilocybin, the prodrug of the psychoactive molecule psilocin, has demonstrated promising results in clinical trials for the treatment of addiction, depression, and post-traumatic stress disorder. The development of a psilocybin production platform in a highly engineerable microbe could lead to
Nenad Manevski et al.
Drug metabolism and disposition: the biological fate of chemicals, 38(3), 386-395 (2009-12-17)
We have examined the glucuronidation of psilocin, a hallucinogenic indole alkaloid, by the 19 recombinant human UDP-glucuronosyltransferases (UGTs) of subfamilies 1A, 2A, and 2B. The glucuronidation of 4-hydroxyindole, a related indole that lacks the N,N-dimethylaminoethyl side chain, was studied as
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