201634

6-Aminofluorescein

• Sinónimos: Fluoresceinamine isomer II
• Fórmula empírica (notación de Hill): C₂₀H₁₃NO₅
• Número de CAS: 51649-83-3
• Peso molecular: 347.32
• Beilstein: 51708
• Número CE: 257-334-7
• Número MDL: MFCD00005051
• Código UNSPSC: 12171500
• ID de la sustancia en PubChem: 24852016
• NACRES: NA.47

Propiedades

• Formulario: powder
• Nivel de calidad: 200
• mp: 285 °C (dec.) (lit.)
• solubilidad: methanol: 1 mg/mL, clear, yellow to very dark yellow-orange
• λmáx.: 495 nm
• aplicaciones: diagnostic assay manufacturing; hematology; histology
• temp. de almacenamiento: room temp
• cadena SMILES: Nc1ccc2C(=O)OC3(c4ccc(O)cc4Oc5cc(O)ccc35)c2c1
• InChI: 1S/C20H13NO5/c21-10-1-4-13-16(7-10)20(26-19(13)24)14-5-2-11(22)8-17(14)25-18-9-12(23)3-6-15(18)20/h1-9,22-23H,21H2
• Clave InChI: YOAWSYSKQHLFPM-UHFFFAOYSA-N

Descripción

Aplicación

6-Aminofluorescein has been demonstrated to be useful fluorescent labeling reagent for fullerene-based liposome nanostructures termed ‘buckysomes′. 6-aminofluorescein dissolved in 0.1 N NaOH can be quantified from a maximum absorbance at 490 nm. Decarboxylated 6-aminofluorescein dissolved 6 N HCl (prepare by constant boiling at 110° C for 24 h) can be quantified from a maximum absorbance at 454 nm. Aldehyde groups are formed by oxidateive damage to proteins, which can be detected by conjugation to decarboxylated 6-aminofluorescein.

6-Aminofluorescein has been used to determine its ability to potentiate the antiviral activity of poly r (A-U).

Otras notas

Note: Do not confuse with fluorescamine.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves