126462
6,7-Dimethyl-2,3-di(2-pyridyl)quinoxaline
98%
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About This Item
Fórmula empírica (notación de Hill):
C20H16N4
Número de CAS:
Peso molecular:
312.37
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de la sustancia en PubChem:
NACRES:
NA.22
Productos recomendados
Nivel de calidad
Ensayo
98%
Formulario
powder
mp
191-193 °C (lit.)
cadena SMILES
Cc1cc2nc(-c3ccccn3)c(nc2cc1C)-c4ccccn4
InChI
1S/C20H16N4/c1-13-11-17-18(12-14(13)2)24-20(16-8-4-6-10-22-16)19(23-17)15-7-3-5-9-21-15/h3-12H,1-2H3
Clave InChI
NACXMBPTPBZQHY-UHFFFAOYSA-N
Categorías relacionadas
Aplicación
6,7-Dimethyl-2,3-di-(2-pyridyl)quinoxaline has been used as an internal standard to investigate the clinical pharmacokinetics of nelfinavir mesylate, a potent inhibitor of HIV-1 protease.
Palabra de señalización
Warning
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Órganos de actuación
Respiratory system
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
dust mask type N95 (US), Eyeshields, Gloves
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E Y Wu et al.
Journal of chromatography. B, Biomedical sciences and applications, 695(2), 373-380 (1997-08-01)
Nelfinavir mesylate, a potent and orally bioavailable inhibitor of HIV-1 protease (Ki=2 nM), has undergone Phase III clinical evaluation in a large population of HIV-positive patients. A high-performance liquid chromatography analytical method was developed to determine the pharmacokinetic parameters of
B Louveau et al.
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