126136

Diethyl methylmalonate

99%

• Sinónimos: Methylmalonic acid diethyl ester
• Fórmula lineal: CH₃CH(COOC₂H₅)₂
• Número de CAS: 609-08-5
• Peso molecular: 174.19
• Beilstein/REAXYS Number: 637028
• EC Number: 210-175-7
• MDL number: MFCD00009162
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847702
• NACRES: NA.22

Propiedades

• assay: 99%
• refractive index: n20/D 1.413 (lit.)
• bp: 198-199 °C (lit.); 78-80 °C/10 mmHg
• density: 1.022 g/mL at 20 °C (lit.)
• SMILES string: CCOC(=O)C(C)C(=O)OCC
• InChI: 1S/C8H14O4/c1-4-11-7(9)6(3)8(10)12-5-2/h6H,4-5H2,1-3H3
• InChI key: UPQZOUHVTJNGFK-UHFFFAOYSA-N

Descripción

General description

Diethyl methylmalonate reacts with 2-cyclohexenone under abnormal Michael conditions form 2-(3-oxocyclohexyl)-2-cyclohexenone. It causes the alkylation of poly(chloromethylstyrene) during pahse transfer catalysis.

Application

Diethyl methylmalonate was used to investigate the effect of direct supplementation of the medium with di-ester of methylmalonate on erythromycin fermentation in Saccharopolyspora erythraea mutB strain.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 179.6 °F - closed cup
• flash_point_c: 82 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter