SML0298

PSNCBAM-1

≥98% (HPLC)

• Synonym(s): N-(4-Chlorophenyl)-N′-[3-[6-(1-pyrrolidinyl)-2-pyridinyl]phenyl]-urea
• Empirical Formula (Hill Notation): C₂₂H₂₁ClN₄O
• CAS Number: 877202-74-9
• Molecular Weight: 392.88
• MDL number: MFCD12756395
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825304
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 15 mg/mL (clear solution)
• storage temp.: 2-8°C
• SMILES string: Clc1ccc(NC(=O)Nc2cccc(c2)-c3cccc(n3)N4CCCC4)cc1
• InChI: 1S/C22H21ClN4O/c23-17-9-11-18(12-10-17)24-22(28)25-19-6-3-5-16(15-19)20-7-4-8-21(26-20)27-13-1-2-14-27/h3-12,15H,1-2,13-14H2,(H2,24,25,28)
• InChI key: HDAYFSFWIPRJSO-UHFFFAOYSA-N

Description

Biochem/physiol Actions

PSNCBAM-1 is an allosteric, non-competitive antagonist of CB-1. The compound blocks the effects of WIN 55212-2 and CP55940, and reduces food intake and weight gain in rats.

Features and Benefits

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H319
• Precautionary Statements: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable